Weight | 226.232 g/mol |
---|---|
Formula | C10H14N2O4 |
Hydrogen Acceptors | 4 |
Hydrogen Donors | 3 |
Aromatic Rings | 0 |
Rotatable Bonds | 4 |
Proxibarbal
Axeen · proxybarbital · Ipronal
2537-29-3, 42013-22-9, 42013-34-3
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- Valofan diastereoisomers: their analysis by high-performance liquid chromatography and interconversion wth proxibarbal in aqueous solution (Journal of Chromatography A, 1979)
- Isomerisation and urinary excretion of proxibarbal and valofan in man; a preliminary study. (European Journal of Drug Metabolism and Pharmacokinetics, 1984)
- Metabolic investigations of proxibarbal [5-allyl-5-(2-hydroxypropyl)barbituric acid] in vitro. (Pharmaceutica Acta Helvetiae, 1980)
- Pharmacokinetics ofl4C-2-allophanyl-2-allyl -gamma-valerolactone: a prodrug of proxibarbal in rats (European Journal of Drug Metabolism and Pharmacokinetics, 1981)
- The Reversible Proxibarbal-Valofan Isomerisation. Part II. Kinetic studies in a biphasic octanol/water system (Helvetica Chimica Acta, 1988)
- The Reversible ProxibarbalValofan Isomerisation. Part I. Kinetic and thermodynamic studies in aqueous solutions (Helvetica Chimica Acta, 1988)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Axeen
- proxybarbital
- Ipronal
- Vasalgin
- Centralagol
-
SMILESCC(CC1(C(=O)NC(=O)NC1=O)CC=C)O
-
InChIKeyVNLMRPAWAMPLNZ-UHFFFAOYSA-N
- Pubchem - Proxibarbal
- Wikipedia - proxibarbal
Proxibarbital (Ipronal) is a barbiturate derivative synthesized in 1956. It has anti-anxiety properties and in contrast to most barbiturates almost without hypnotic action. It was also used in the treatment of migraine headaches in a similar manner to butalbital.
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