| Weight | 1022.239 g/mol |
|---|---|
| Formula | C53H67N9O10S |
| Hydrogen Acceptors | 14 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 10 |
Quinupristin (120138-50-3)
Score:
#174 in Microbiology
,
#1829 in Biology
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- In Vitro Activities of Daptomycin, Vancomycin, Linezolid, and Quinupristin-Dalfopristin against Staphylococci and Enterococci, Including Vancomycin- Intermediate and -Resistant Strains (Antimicrobial Agents and Chemotherapy, 2000)
- The efficacy and safety of quinupristin/dalfopristin for the treatment of infections caused by vancomycin-resistant Enterococcus faecium (Journal of Antimicrobial Chemotherapy, 1999)
- Treatment of Gram-positive nosocomial pneumonia: prospective randomized comparison of quinupristin/dalfopristin versus vancomycin. (American Journal of Respiratory and Critical Care Medicine, 2000)
- Antimicrobial Activity of Quinupristin-Dalfopristin (RP 59500, Synercid) Tested against Over 28,000 Recent Clinical Isolates from 200 Medical Centers in the United States and Canada (Diagnostic Microbiology and Infectious Disease, 1998)
- Quinupristin-Dalfopristin and Linezolid: Evidence and Opinion (Clinical Infectious Diseases, 2003)
- Treatment of methicillin-resistant Staphylococcus aureus infections with quinupristindalfopristin in patients intolerant of or failing prior therapy (Journal of Antimicrobial Chemotherapy, 2000)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCCC1C(=O)N2CCCC2C(=O)N(C(C(=O)N3CC(C(=O)CC3C(=O)NC(C(=O)OC(C(C(=O)N1)NC(=O)C4=C(C=CC=N4)O)C)C5=CC=CC=C5)CSC6CN7CCC6CC7)CC8=CC=C(C=C8)N(C)C)C
-
InChIKeyWTHRRGMBUAHGNI-UHFFFAOYSA-N
- Pubchem - Quinupristin
- Wikipedia - quinupristin
Quinupristin is an antibiotic, often used in combination with dalfopristin under the trade name Synercid. It is active against Gram-positive bacteria, atypical but not Gram negatives. They inhibit protein synthesis of the cells.
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