Score: #147 in Biochemistry , #632 in Biology , #674 in Chemistry

  Pharmaceutical

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Suppliers

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  50 mg
  $50.00

  1 g
  $55.00

  5 g
  $120.00

  50 g
  $150.00

  100 g
  $235.00

Most-cited Publications

• THE EFFECT OF SPIRONOLACTONE ON MORBIDITY AND MORTALITY IN PATIENTS WITH SEVERE HEART FAILURE (The New England Journal of Medicine, 1999)
• Rates of Hyperkalemia after Publication of the Randomized Aldactone Evaluation Study (The New England Journal of Medicine, 2004)
• Limitation of Excessive Extracellular Matrix Turnover May Contribute to Survival Benefit of Spironolactone Therapy in Patients With Congestive Heart Failure Insights From the Randomized Aldactone Evaluation Study (RALES) (Circulation, 2000)
• Spironolactone for Heart Failure with Preserved Ejection Fraction (The New England Journal of Medicine, 2014)
• Effect of Spironolactone on Blood Pressure in Subjects With Resistant Hypertension (Hypertension, 2007)
• Spironolactone Increases Nitric Oxide Bioactivity, Improves Endothelial Vasodilator Dysfunction, and Suppresses Vascular Angiotensin I/Angiotensin II Conversion in Patients With Chronic Heart Failure (Circulation, 2000)

Areas of Application

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Trends

Alternate Names

• Aldactone
• Spirolactone
• NovoSpiroton
• Aldactone A
• Pfizer Brand of Spironolactone
• Verospirone
• Novopharm Brand of Spironolactone
• Jenaspiron
• Pharmafrid Brand of Spironolactone
• Spirono-Isis
• Veroshpiron
• SC9420
• Roche Brand of Spironolactone
• ct Arzneimittel Brand of Spironolactone
• Espironolactona Alter
• Mundogen Brand of Spironolactone
• Spirobeta
• Merck dura Brand of Spironolactone
• Spiro L.U.T.
• betapharm Brand of Spironolactone
• Espironolactona Mundogen
• Aquareduct
• Spirono Isis
• SC-9420
• Flumach
• SC 9420
• ct-Arzneimittel Brand of Spironolactone
• Dexo Brand of Spironolactone
• Searle Brand of Spironolactone
• Jenapharm Brand of Spironolactone
• Generosan Brand of Spironolactone
• Novo-Spiroton
• Alpharma Brand of Spironolactone
• spiro von ct
• Spironone
• Practon
• Spirogamma
• duraspiron
• Mayoly-Spindler Brand of Spironolactone
• Azupharma Brand of Spironolactone
• Alphapharm Brand of Spironolactone
• Novo Spiroton
• Spirolang
• Hormosan Brand of Spironolactone
• Spirospare
• Frumikal
• Ashbourne Brand of Spironolactone
• Wrwag Brand of Spironolactone
• Alter Brand of Spironolactone
• Cardel Brand of Spironolactone
• Spiractin
• Verospiron
• SMILES
  CC(=O)SC1CC2=CC(=O)CCC2(C3C1C4CCC5(C4(CC3)C)CCC(=O)O5)C
• InChIKey
  LXMSZDCAJNLERA-UHFFFAOYSA-N

External Links

• Pubchem - spironolactone
• Wikipedia - spironolactone
  Spironolactone, sold under the brand name Aldactone among others, is a medication that is primarily used to treat fluid build-up due to heart failure, liver scarring, or kidney disease. It is also used in the treatment of high blood pressure, low blood potassium that does not improve with supplementation, early puberty in boys, acne and excessive hair growth in women, and as a part of feminizing hormone therapy in transgender women. Spironolactone is taken by mouth.

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