| Weight | 465.568 g/mol |
|---|---|
| Formula | C23H31NO7S |
| Hydrogen Acceptors | 7 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 12 |
Sulprostone (60325-46-4)
Schering brand of sulprostone · CP-34089 · 5Z,13E-18R,11R,12R,15R- dihydroxy-9-oxo-16-phenoxy-17,18,19,20-tetranor- 5,13-prostadienoic acid methylsulfonylamide
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- Sigma-Aldrich - Sulprostone162.00 - 576.00 USD
- Fisher Scientific - Search for Sulprostone
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- The prostaglandin E2 analogue sulprostone antagonizes vasopressin-induced antidiuresis through activation of Rho (Journal of Cell Science, 2003)
- Comparison of the mode of action of prostaglandin E2 (PGE2) and sulprostone, a PGE2-derivative, on the lower urinary tract in healthy women. A urodynamic study. (Urological Research, 1990)
- Practical use of sulprostone in the treatment of hemorrhages during delivery (Journal De Gynecologie Obstetrique Et Biologie De La Reproduction, 1995)
- A randomized comparison of oxytocin, sulprostone and placebo in the management of the third stage of labour (British Journal of Obstetrics and Gynaecology, 1991)
- Cardiac arrest associated with sulprostone use during caesarean section (Anaesthesia and Intensive Care, 1998)
- Conservative management of ectopic pregnancy: prospective randomized clinical trial of methotrexate versus prostaglandin sulprostone by combined transvaginal and systemic administration (Fertility and Sterility, 1991)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Schering brand of sulprostone
- CP-34089
- 5Z,13E-18R,11R,12R,15R- dihydroxy-9-oxo-16-phenoxy-17,18,19,20-tetranor- 5,13-prostadienoic acid methylsulfonylamide
- 34.089 Pfizer
- ZK-57671
- Nalador
- 16-phenoxy-omega-17,18,19,20-tetranor-PGE2 methylsulfonylamide
- 16-phenoxytetranor-PGE2 methylsulfonylamide
- SHB 286
- sulproston
-
SMILESCS(=O)(=O)NC(=O)CCCC=CCC1C(C(CC1=O)O)C=CC(COC2=CC=CC=C2)O
-
InChIKeyUQZVCDCIMBLVNR-UHFFFAOYSA-N
- Pubchem - Sulprostone
- Wikipedia - sulprostone
Sulprostone is an analogue of prostaglandin E2 (PGE2) that has oxytocic activity in assays of rat kidney cells and tissues. There are four known receptors which mediate various but often different cellular and tissue responses to PGE2: prostaglandin EP1 receptor, prostaglandin EP2 receptor, prostaglandin EP3 receptor, and prostaglandin EP4 receptor. Sulprosotone binds to and activates the prostaglandin EP3 receptor with far greater efficacy than the other PGE2 receptors and also has the advantage of being relatively resistant, compared with PGE2, to becoming metabolically degraded.
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