| Weight | 337.379 g/mol |
|---|---|
| Formula | C19H19N3O3 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 1 |
Talampanel (161832-65-1)
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- Sigma-Aldrich - Talampanel105.50 - 425.50 USD
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- Talampanel With Standard Radiation and Temozolomide in Patients With Newly Diagnosed Glioblastoma: A Multicenter Phase II Trial (Journal of Clinical Oncology, 2009)
- A phase II trial of talampanel in subjects with amyotrophic lateral sclerosis. (Amyotrophic Lateral Sclerosis, 2010)
- A crossover, add-on trial of talampanel in patients with refractory partial seizures. (Neurology, 2002)
- Talampanel, a New Antiepileptic Drug: Single- and Multiple-dose Pharmacokinetics and Initial 1-Week Experience in Patients with Chronic Intractable Epilepsy (Epilepsia, 2003)
- Phase 2 Trial of Talampanel, a Glutamate Receptor Inhibitor, for Adults With Recurrent Malignant Gliomas (Cancer, 2010)
- Talampanel, a Novel Noncompetitive AMPA Antagonist, is Neuroprotective after Traumatic Brain Injury in Rats (Journal of Neurotrauma, 2001)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1CC2=CC3=C(C=C2C(=NN1C(=O)C)C4=CC=C(C=C4)N)OCO3
-
InChIKeyJACAAXNEHGBPOQ-UHFFFAOYSA-N
- Pubchem - Talampanel
- Wikipedia - talampanel
Talampanel (INN) (code names GYKI 537773, LY300164) is a drug which has been investigated for the treatment of epilepsy, malignant gliomas and amyotrophic lateral sclerosis (ALS). As of May 2010, results from the trial for ALS have been found negative. Talampanel is not currently under development.
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