| Weight | 417.387 g/mol |
|---|---|
| Formula | C21H18F3N3O3 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 3 |
Temafloxacin (108319-06-8)
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- Temafloxacin Syndrome: Review of 95 Cases (Clinical Infectious Diseases, 1994)
- Comparative antibacterial activities of temafloxacin hydrochloride (A-62254) and two reference fluoroquinolones. (Antimicrobial Agents and Chemotherapy, 1987)
- Susceptibilities of penicillin-susceptible and -resistant strains of Streptococcus pneumoniae to RP 59500, vancomycin, erythromycin, PD 131628, sparfloxacin, temafloxacin, win 57273, ofloxacin, and ciprofloxacin. (Antimicrobial Agents and Chemotherapy, 1992)
- Activities of sparfloxacin, azithromycin, temafloxacin, and rifapentine compared with that of clarithromycin against multiplication of Mycobacterium avium complex within human macrophages. (Antimicrobial Agents and Chemotherapy, 1991)
- Comparative activity of ciprofloxacin, ofloxacin, sparfloxacin, temafloxacin, CI-960, CI-990, and WIN 57273 against anaerobic bacteria. (Antimicrobial Agents and Chemotherapy, 1992)
- Effect of pH variation on the susceptibility ofHelicobacter pylori to three macrolide antimicrobial agents and temafloxacin (European Journal of Clinical Microbiology & Infectious Diseases, 1993)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1CN(CCN1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4=C(C=C(C=C4)F)F)F
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- Pubchem - Temafloxacin
- Wikipedia - temafloxacin
Temafloxacin (marketed by Abbott Laboratories as Omniflox) is a fluoroquinolone antibiotic drug which was withdrawn from sale in the United States shortly after its approval in 1992 because of serious adverse effects resulting in three deaths. It is not marketed in Europe.
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