| Weight | 194.154 g/mol |
|---|---|
| Formula | C6H6N6O2 |
| Hydrogen Acceptors | 7 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 1 |
temozolomide (85622-93-1)
Score:
#97 in Neurology
,
#487 in Neuroscience
,
#838 in Biochemistry
,
#2249 in Biology
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- Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma (The New England Journal of Medicine, 2005)
- MGMT Gene Silencing and Benefit from Temozolomide in Glioblastoma (The New England Journal of Medicine, 2005)
- Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. (Lancet Oncology, 2009)
- Randomized Phase III Study of Temozolomide Versus Dacarbazine in the Treatment of Patients With Advanced Metastatic Malignant Melanoma (Journal of Clinical Oncology, 2000)
- Bevacizumab plus RadiotherapyTemozolomide for Newly Diagnosed Glioblastoma (The New England Journal of Medicine, 2014)
- A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse. (British Journal of Cancer, 2000)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCN1C(=O)N2C=NC(=C2N=N1)C(=O)N
-
InChIKeyBPEGJWRSRHCHSN-UHFFFAOYSA-N
- Pubchem - temozolomide
- Wikipedia - temozolomide
Temozolomide (TMZ; brand names Temodar and Temodal and Temcad) is an oral chemotherapy drug. It is an alkylating agent used as a treatment of some brain cancers; as a second-line treatment for astrocytoma and a first-line treatment for glioblastoma multiforme.
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