Weight | 265.25 g/mol |
---|---|
Formula | C10H7N3O4S |
Hydrogen Acceptors | 6 |
Hydrogen Donors | 2 |
Aromatic Rings | 2 |
Rotatable Bonds | 3 |
Tizoxanide (173903-47-4)
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- Nitazoxanide, tizoxanide and other thiazolides are potent inhibitors of hepatitis B virus and hepatitis C virus replication. (Antiviral Research, 2008)
- In vitro evaluation of activities of nitazoxanide and tizoxanide against anaerobes and aerobic organisms. (Antimicrobial Agents and Chemotherapy, 1996)
- Efficacy of nitazoxanide, tizoxanide and tizoxanide glucuronide against Cryptosporidium parvum development in sporozoite-infected HCT-8 enterocytic cells (Journal of Antimicrobial Chemotherapy, 2000)
- Activities of Tizoxanide and Nitazoxanide Compared to Those of Five Other Thiazolides and Three Other Agents against Anaerobic Species (Antimicrobial Agents and Chemotherapy, 2006)
- Potential for Hepatitis C Virus Resistance to Nitazoxanide or Tizoxanide (Antimicrobial Agents and Chemotherapy, 2008)
- Synthesis of benzologues of Nitazoxanide and Tizoxanide: A comparative study of their in vitro broad-spectrum antiprotozoal activity (Bioorganic & Medicinal Chemistry Letters, 2011)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1=CC=C(C(=C1)C(=O)NC2=NC=C(S2)[N+](=O)[O-])O
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InChIKeyFDTZUTSGGSRHQF-UHFFFAOYSA-N
- Pubchem - Tizoxanide
- Wikipedia - tizoxanide
Tizoxanide, also known as desacetyl-nitazoxanide, is a thiazolide and an antiparasitic agent that occurs as a metabolite of nitazoxanide in humans through hydrolysis. Tizoxanide may undergo further metabolism via conjugation into tizoxanide glucuronide.
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