| Weight | 302.374 g/mol |
|---|---|
| Formula | C17H22N2O3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 6 |
trichostatin A (58880-19-6)
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- Sigma-Aldrich - trichostatin A153.50 - 502.00 USD
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Predict GHS Hazards for Any Chemical in silico.
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SMILESCC(C=C(C)C=CC(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C
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InChIKeyRTKIYFITIVXBLE-UHFFFAOYSA-N
- Pubchem - trichostatin A
- Wikipedia - trichostatin A
Trichostatin A (TSA) is an organic compound that serves as an antifungal antibiotic and selectively inhibits the class I and II mammalian histone deacetylase (HDAC) families of enzymes, but not class III HDACs (i.e., sirtuins). TSA inhibits the eukaryotic cell cycle during the beginning of the growth stage. TSA can be used to alter gene expression by interfering with the removal of acetyl groups from histones (histone deacetylases, HDAC) and therefore altering the ability of DNA transcription factors to access the DNA molecules inside chromatin.
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trichostatin A
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