| Weight | 277.408 g/mol |
|---|---|
| Formula | C17H27NO2 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 5 |
venlafaxine (93413-69-5)
Score:
#85 in Neuroscience
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#425 in Biology
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#441 in Chemistry
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- Remission rates during treatment with venlafaxine or selective serotonin reuptake inhibitors (British Journal of Psychiatry, 2001)
- Bupropion-SR, Sertraline, or Venlafaxine-XR after Failure of SSRIs for Depression (The New England Journal of Medicine, 2006)
- Venlafaxine in management of hot flashes in survivors of breast cancer: a randomised controlled trial (The Lancet, 2000)
- Comparative Affinity of Duloxetine and Venlafaxine for Serotonin and Norepinephrine Transporters in vitro and in vivo, Human Serotonin Receptor Subtypes, and Other Neuronal Receptors (Neuropsychopharmacology, 2001)
- The Neural Substrates of Affective Processing in Depressed Patients Treated With Venlafaxine (American Journal of Psychiatry, 2003)
- Switching to Another SSRI or to Venlafaxine With or Without Cognitive Behavioral Therapy for Adolescents With SSRI-Resistant Depression: The TORDIA Randomized Controlled Trial (JAMA, 2008)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O
-
InChIKeyPNVNVHUZROJLTJ-UHFFFAOYSA-N
- Pubchem - venlafaxine
- Wikipedia - venlafaxine
Venlafaxine, sold under the brand name Effexor among others, is an antidepressant of the selective serotonin-norepinephrine reuptake inhibitor (SNRI) class. This means it increases the concentrations of the neurotransmitters serotonin and norepinephrine in the body and the brain. First introduced by Wyeth in 1993, now marketed by Pfizer, it is licensed for the treatment of major depressive disorder (MDD), generalised anxiety disorder (GAD), panic disorder and social phobia.
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Synthesis
ANISOLE
+
Reactant
(Friedel-Crafts alkylation)
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