| Weight | 147.094 g/mol |
|---|---|
| Formula | C2H5N5O3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 2 |
1-Methyl-3-nitro-1-nitrosoguanidine (70-25-7)
MNNG · N Methyl N' nitro N nitrosoguanidine · Methylnitronitrosoguanidine
Score:
#3 in Molecular and cellular biology
,
#130 in Biochemistry
,
#571 in Biology
,
#607 in Chemistry
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- TCI - 1-Methyl-3-nitro-1-nitrosoguanidine77.00 - 272.00 USD
- A new chemical mutagen for bacteria, 1-methyl-3-nitro-1-nitrosoguanidine (Biochemical and Biophysical Research Communications, 1960)
- Induction of mitotic gene conversion with nitrous acid, 1-methyl-3-nitro-1-nitrosoguanidine and other alkylating agents in Saccharomyces cerevisiae (Molecular Genetics and Genomics, 1967)
- Detection of MNNG-induced DNA lesions in mammalian cells; validation of comet assay against DNA unwinding technique, alkaline elution of DNA and chromosomal aberrations (Mutation Research-dna Repair, 1997)
- Molecular analysis of complex human cell populations: mutational spectra of MNNG and ICR-191 (Mutation Research, 1990)
- Pretreatment of normal human fibroblasts and human colon carcinoma cells with MNNG allows chloroethylnitrosourea to produce DNA interstrand crosslinks not observed in cells treated with chloroethylnitrosourea alone (Carcinogenesis, 1983)
- MNNG-induced gastric carcinoma in ferrets infected with Helicobacter mustelae (Carcinogenesis, 1993)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H302: Harmful if swallowed
Warning Acute toxicity, oral - Category 4 - H315: Causes skin irritation
Warning Skin corrosion/irritation - Category 2 - H317: May cause an allergic skin reaction
Warning Sensitization, Skin - Category 1 - H332: Harmful if inhaled
Warning Acute toxicity, inhalation - Category 4 - H341: Suspected of causing genetic defects
Warning Germ cell mutagenicity - Category 2 - H411: Toxic to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard - Category 2 - MNNG
- N Methyl N' nitro N nitrosoguanidine
- Methylnitronitrosoguanidine
- Nitrosomethylnitroguanidine
- N-Methyl-N'-nitro-N-nitrosoguanidine
- Nitrosonitromethylguanidine
- Methylnitrosonitroguanidine
-
SMILESCN(C(=N[N+](=O)[O-])N)N=O
-
InChIKeyVZUNGTLZRAYYDE-UHFFFAOYSA-N
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Synthesis
Methylboronic acid
+
Reactant
(Chan-Lam coupling reaction)
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