| Weight | 256.092 g/mol |
|---|---|
| Formula | C10H7Cl2N3O |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 0 |
anagrelide (68475-42-3)
Agrylin · anagrelide hydrochloride · 6,7-dichloro-1,5-dihydroimidazo(2,1-b)quinazolin-2(3H)-one hydrochloride
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- Hydroxyurea Compared with Anagrelide in High-Risk Essential Thrombocythemia (The New England Journal of Medicine, 2005)
- Long-term use of anagrelide in young patients with essential thrombocythemia (Blood, 2001)
- Anagrelide: A New Drug for Treating Thrombocytosis (The New England Journal of Medicine, 1988)
- Anagrelide compared with hydroxyurea in WHO-classified essential thrombocythemia: the ANAHYDRET Study, a randomized controlled trial (Blood, 2013)
- The effects of anagrelide on human megakaryocytopoiesis (British Journal of Haematology, 1997)
- Anagrelide for control of thrombocythemia in polycythemia and other myeloproliferative disorders. (Seminars in Hematology, 1997)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Agrylin
- anagrelide hydrochloride
- 6,7-dichloro-1,5-dihydroimidazo(2,1-b)quinazolin-2(3H)-one hydrochloride
- Agrelin
- imidazo(2,1-b)quinazolin-2(3H)-one, 6,7-dichloro-1,5-dihydro-, monohydrochloride
- BL 4162A
-
SMILESC1C2=C(C=CC(=C2Cl)Cl)NC3=NC(=O)CN31
-
InChIKeyOTBXOEAOVRKTNQ-UHFFFAOYSA-N
- Pubchem - anagrelide
- Wikipedia - anagrelide
Anagrelide (Agrylin/Xagrid, Shire and Thromboreductin, AOP Orphan Pharmaceuticals AG) is a drug used for the treatment of essential thrombocytosis (ET; essential thrombocythemia), or overproduction of blood platelets. It also has been used in the treatment of chronic myeloid leukemia. Anagrelide controlled release (GALE-401) is in phase III clinical trials by Galena Biopharma for the treatment of ET.
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anagrelide
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