Weight | 292.553 g/mol |
---|---|
Formula | C10H8Cl3N3O |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 1 |
Aromatic Rings | 1 |
Rotatable Bonds | 0 |
ANAGRELIDE HYDROCHLORIDE (58579-51-4)
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- Pharmacokinetics and tolerability of anagrelide hydrochloride in young (18 - 50 years) and elderly ( 65 years) patients with essential thrombocythemia. (Principles and Practice of Constraint Programming, 2012)
- Anagrelide hydrochloride and ruxolitinib for treatment of polycythemia vera. (Expert Opinion on Pharmacotherapy, 2015)
- Development and Validation of a Stability-Indicating RP-HPLC Method for the Quantitative Analysis of Anagrelide Hydrochloride. (Scientia Pharmaceutica, 2012)
- Acute pancreatitis as a side effect of anagrelide hydrochloride hydrate: a case report. (Annals of Hematology, 2016)
- Method for the production of anagrelide hydrochloride (2005)
- Process for the Manufacture of Anagrelide Hydrochloride Monohydrate (2008)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1C2=C(C=CC(=C2Cl)Cl)NC3=NC(=O)CN31.Cl
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InChIKeyTVWRQCIPWUCNMI-UHFFFAOYSA-N
- Pubchem - ANAGRELIDE HYDROCHLORIDE
- Wikipedia - anagrelide hydrochloride
Anagrelide (Agrylin/Xagrid, Shire and Thromboreductin, AOP Orphan Pharmaceuticals AG) is a drug used for the treatment of essential thrombocytosis (ET; essential thrombocythemia), or overproduction of blood platelets. It also has been used in the treatment of chronic myeloid leukemia. Anagrelide controlled release (GALE-401) is in phase III clinical trials by Galena Biopharma for the treatment of ET.
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