| Weight | 298.426 g/mol |
|---|---|
| Formula | C20H26O2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 0 |
ATAMESTANE (96301-34-7)
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- Effects of Dehydroepiandrosterone and Atamestane Supplementation on Frailty in Elderly Men (The Journal of Clinical Endocrinology and Metabolism, 2006)
- Placebo Controlled Double-blind Study to Test the Efficacy of the Aromatase Inhibitor Atamestane in Patients with Benign Prostatic Hyperplasia not Requiring Operation * (The Journal of Urology, 1995)
- Estrogen reduction by aromatase inhibition for benign prostatic hyperplasia: Results of a double-blind, placebo-controlled, randomized clinical trial using two doses of the aromatase-inhibitor atamestane (The Prostate, 1996)
- Comparison of the effects of the irreversible aromatase inhibitor exemestane with atamestane and MDL 18962 in rats with DMBA-induced mammary tumours (European Journal of Cancer and Clinical Oncology, 1991)
- Atamestane: an aromatase inhibitor for the treatment of benign prostatic hyperplasia. A short review. (The Journal of Steroid Biochemistry and Molecular Biology, 1993)
- Atamestane, a New Aromatase Inhibitor for the Management of Benign Prostatic Hyperplasia (Journal of Andrology, 1991)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1=CC(=O)C=C2C1(C3CCC4(C(C3CC2)CCC4=O)C)C
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InChIKeyPEPMWUSGRKINHX-UHFFFAOYSA-N
- Pubchem - ATAMESTANE
- Wikipedia - atamestane
Atamestane (developmental code name SH-489), also known as metandroden, as well as 1-methylandrosta-1,4-diene-3,17-dione, is a steroidal aromatase inhibitor that was studied in the treatment of cancer. It blocks the production of estrogen in the body. The drug is selective, competitive, and irreversible in its inhibition of aromatase.
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