Weight | 357.419 g/mol |
---|---|
Formula | C22H22F3N |
Hydrogen Acceptors | 1 |
Hydrogen Donors | 1 |
Aromatic Rings | 3 |
Rotatable Bonds | 6 |
Cinacalcet (226256-56-0)
Score:
#506 in Biochemistry
,
#1592 in Biology
,
#1869 in Chemistry
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- Cinacalcet for secondary hyperparathyroidism in patients receiving hemodialysis (The New England Journal of Medicine, 2004)
- Effect of cinacalcet on cardiovascular disease in patients undergoing dialysis (The New England Journal of Medicine, 2012)
- Effects of the calcimimetic cinacalcet HCl on cardiovascular disease, fracture, and health-related quality of life in secondary hyperparathyroidism (Kidney International, 2005)
- Cinacalcet Hydrochloride Maintains Long-Term Normocalcemia in Patients with Primary Hyperparathyroidism (The Journal of Clinical Endocrinology and Metabolism, 2005)
- Cinacalcet HCl, an Oral Calcimimetic Agent for the Treatment of Secondary Hyperparathyroidism in Hemodialysis and Peritoneal Dialysis: A Randomized, Double-Blind, Multicenter Study (Journal of The American Society of Nephrology, 2005)
- The ADVANCE study: a randomized study to evaluate the effects of cinacalcet plus low-dose vitamin D on vascular calcification in patients on hemodialysis (Nephrology Dialysis Transplantation, 2011)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(C1=CC=CC2=CC=CC=C21)NCCCC3=CC(=CC=C3)C(F)(F)F
-
InChIKeyVDHAWDNDOKGFTD-UHFFFAOYSA-N
- Pubchem - Cinacalcet
- Wikipedia - cinacalcet
Cinacalcet (INN) is a drug that acts as a calcimimetic (i.e. it mimics the action of calcium on tissues) by allosteric activation of the calcium-sensing receptor that is expressed in various human organ tissues (Van Wagenen et al. (2001), U.S.
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