| Weight | 341.433 g/mol |
|---|---|
| Formula | C15H23N3O4S |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 3 |
CYCLACILLIN (3485-14-1)
Wy-4508 · Aminocyclohexylpenicillin · Ciclacillin
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- Single-dose therapy for cystitis in women. A comparison of trimethoprim-sulfamethoxazole, amoxicillin, and cyclacillin. (JAMA, 1985)
- The effect of antimicrobial agents on human faecal flora: studies with cephalexin, cyclacillin and clindamycin. (1974)
- The therapeutic effects of cyclacillin in acute sinusitis: in vitro and in vivo correlations in a placebo-controlled study. (Current Medical Research and Opinion, 1973)
- Intestinal absorption mechanism of amphoteric -lactam antibiotics. II. Michaelis-Menten kinetics of cyclacillin absorption and its pharmacokinetic analysis in rats (Journal of Pharmaceutical Sciences, 1981)
- Comparison of cyclacillin and amoxicillin for therapy for acute maxillary sinusitis. (Antimicrobial Agents and Chemotherapy, 1986)
- Oral cyclacillin interacts with the absorption of oral ampicillin, amoxycillin, and bacampicillin. (European Journal of Clinical Pharmacology, 1985)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Wy-4508
- Aminocyclohexylpenicillin
- Ciclacillin
- Wy4508
- Wy 4508
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SMILESCC1(C(N2C(S1)C(C2=O)NC(=O)C3(CCCCC3)N)C(=O)O)C
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InChIKeyHGBLNBBNRORJKI-UHFFFAOYSA-N
- Pubchem - CYCLACILLIN
- Wikipedia - cyclacillin
Ciclacillin (INN) or cyclacillin (USAN), trade names Cyclapen, Cyclapen-W, Vastcillin, and others, is an aminopenicillin antibiotic. Its spectrum of activity is similar to that of ampicillin, although it is less susceptible to beta-lactamases than ampicillin and has much higher bioavailability. A large randomized, double-blind clinical trial published in 1978 also showed that ciclacillin is associated with significantly fewer and milder adverse effects than ampicillin; later studies seemed to confirm this improved tolerability, at least in children.
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CYCLACILLIN
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