| Weight | 182.187 g/mol |
|---|---|
| Formula | C6H10N6O |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 3 |
dacarbazine (4342-03-4)
DIC · DTIC · ICDT
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#336 in Physics
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#960 in Chemistry
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- Ipilimumab plus dacarbazine for previously untreated metastatic melanoma (The New England Journal of Medicine, 2011)
- Randomized Phase III Study of Temozolomide Versus Dacarbazine in the Treatment of Patients With Advanced Metastatic Malignant Melanoma (Journal of Clinical Oncology, 2000)
- Phase III Multicenter Randomized Trial of the Dartmouth Regimen Versus Dacarbazine in Patients With Metastatic Melanoma (Journal of Clinical Oncology, 1999)
- Bcl-2 Antisense (oblimersen sodium) Plus Dacarbazine in Patients With Advanced Melanoma: The Oblimersen Melanoma Study Group (Journal of Clinical Oncology, 2006)
- Dacarbazine (DTIC) versus vaccination with autologous peptide-pulsed dendritic cells (DC) in first-line treatment of patients with metastatic melanoma: a randomized phase III trial of the DC study group of the DeCOG (Annals of Oncology, 2006)
- Fotemustine compared with dacarbazine in patients with disseminated malignant melanoma: a phase III study. (Journal of Clinical Oncology, 2004)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - DIC
- DTIC
- ICDT
- Decarbazine
- Dimethyl Triazeno Imidazole Carboxamide
- NSC 45388
- DTIC Dome
- DTICDome
- Biocarbazine
- NSC-45388
- Deticene
- Dimethyl Imidazole Carboxamide
- NSC45388
- 5-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide
- DTIC-Dome
-
SMILESCN(C)NN=C1C(=NC=N1)C(=O)N
-
InChIKeyOMJKFYKNWZZKTK-UHFFFAOYSA-N
- Pubchem - dacarbazine
- Wikipedia - dacarbazine
Dacarbazine (DTIC), also known as imidazole carboxamide, is a chemotherapy medication used in the treatment of melanoma and Hodgkin's lymphoma. For Hodgkin's it is often used together with vinblastine, bleomycin, and doxorubicin. It is given by injection into a vein.
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