| Weight | 379.5 g/mol |
|---|---|
| Formula | C24H29NO3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 6 |
donepezil (120014-06-4)
Aricept · donepezil hydrochloride · E2020
Score:
#52 in Neurology
,
#261 in Neuroscience
,
#1197 in Biology
,
#1371 in Chemistry
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- A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease (Neurology, 1998)
- Vitamin E and Donepezil for the Treatment of Mild Cognitive Impairment (The New England Journal of Medicine, 2005)
- Memantine treatment in Patients with moderate to Severe Alzheimer disease already receiving donepezil: A randomized controlled trial (JAMA, 2004)
- Long-term donepezil treatment in 565 patients with Alzheimer's disease (AD2000): randomised double-blind trial (The Lancet, 2004)
- Donepezil Improves Cognition and Global Function in Alzheimer Disease A 15-Week, Double-blind, Placebo-Controlled Study (JAMA Internal Medicine, 1998)
- A 1-year, randomized, placebo-controlled study of donepezil in patients with mild to moderate AD (Neurology, 2001)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Aricept
- donepezil hydrochloride
- E2020
- Eranz
- E 2020
- 1-benzyl-4-((5,6-dimethoxy-1-indanon)-2-yl)methylpiperidine hydrochloride
- donepezilium oxalate trihydrate
- E-2020
-
SMILESCOC1=C(C=C2C(=C1)CC(C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC
-
InChIKeyADEBPBSSDYVVLD-UHFFFAOYSA-N
- Pubchem - donepezil
- Wikipedia - donepezil
Donepezil, marketed under the trade name Aricept, is a medication used in the palliative treatment of Alzheimer's disease. Donepezil is used to improve cognition and behavior of people with Alzheimer's, but does not slow the progression of or cure the disease. Common side effects include loss of appetite, gastrointestinal upset, diarrhea, difficulty sleeping, vomiting, or muscle cramping.
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donepezil
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