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Suppliers

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  10 mg
  $50.00

  25 mg
  $110.00

  50 mg
  $210.00

  100 mg
  $395.00

  1 g
  $995.00

Most-cited Publications

• The safety of a drospirenone-containing oral contraceptive: final results from the European Active Surveillance study on Oral Contraceptives based on 142,475 women-years of observation (Contraception, 2007)
• Drospirenone: pharmacology and pharmacokinetics of a unique progestogen (Contraception, 2000)
• Efficacy of a new low-dose oral contraceptive with drospirenone in premenstrual dysphoric disorder (Obstetrics & Gynecology, 2005)
• Effects of a new oral contraceptive containing an antimineralocorticoid progestogen, drospirenone, on the renin-aldosterone system, body weight, blood pressure, glucose tolerance, and lipid metabolism. (The Journal of Clinical Endocrinology and Metabolism, 1995)
• Risk of non-fatal venous thromboembolism in women using oral contraceptives containing drospirenone compared with women using oral contraceptives containing levonorgestrel: case-control study using United States claims data. (BMJ, 2011)
• The novel progestin drospirenone and its natural counterpart progesterone: Biochemical profile and antiandrogenic potential (Contraception, 1996)

Areas of Application

Safety

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Trends

Alternate Names

• ZK30595
• 6beta,7beta,15beta,16beta-dimethylen-3-oxo-17alpha-pregn-4-en-21,17-carbolacton
• ZK 30595
• 1,2-dihydro-spirorenone
• dihydrospirorenone
• 1,2-dihydrospirorenone
• SMILES
  CC12CCC(=O)C=C1C3CC3C4C2CCC5(C4C6CC6C57CCC(=O)O7)C
• InChIKey
  METQSPRSQINEEU-UHFFFAOYSA-N

Estimated Properties

Boiling Point	439.13 C	EPA T.E.S.T.
Density	1.23 g/cm3	EPA T.E.S.T.
Flash Point	208.96 C	EPA T.E.S.T.
Water Solubility	4.26 mg/L	EPA T.E.S.T.

External Links

• Pubchem - Drospirenone
• Wikipedia - drospirenone
  Drospirenone is a progestin used in birth control pills and in menopausal hormone therapy for the treatment of menopausal symptoms. In addition to its progestogenic activity, it also has antiandrogenic and antimineralocorticoid activity. It is sold as a combined birth control pill under the brand names Yasmin (US, EU, Latin America), Jasmine (France), Yarina (Russia) in a dosage containing drospirenone 3mg/ethinylestradiol 30g.

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