Weight | 249.317 g/mol |
---|---|
Formula | C16H15N3 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 1 |
Aromatic Rings | 2 |
Rotatable Bonds | 0 |
epinastine
WAL 801 CL · WAL-80 Cl · Flurinol
134507-58-7, 134507-57-6, 80012-43-7
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- A double-blind, single-dose, crossover comparison of cetirizine, ebastine, epinastine, fexofenadine, terfenadine, and loratadine versus placebo: suppression of histamine-induced wheal and flare response for 24 h in healthy male subjects (Allergy, 1999)
- Epinastine, a highly specific antagonist of insect neuronal octopamine receptors. (European Journal of Pharmacology, 1998)
- Efficacy and tolerability of ophthalmic epinastine assessed using the conjunctival antigen challenge model in patients with a history of allergic conjunctivitis. (Clinical Therapeutics, 2004)
- Efficacy and tolerability of ophthalmic epinastine: a randomized, double-masked, parallel-group, active- and vehicle-controlled environmental trial in patients with seasonal allergic conjunctivitis. (Clinical Therapeutics, 2004)
- In vitro and in vivo studies of the non-sedating antihistamine epinastine (Drug Research, 1988)
- Clinical efficacy of olopatadine vs epinastine ophthalmic solution in the conjunctival allergen challenge model (Current Medical Research and Opinion, 2004)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - WAL 801 CL
- WAL-80 Cl
- Flurinol
- 3-amino-9,13b-dihydro-1H-benz(c,f)imidazo(1,5a)azepine
- WAL 801
- epinastine hydrochloride
- WAL 801CL
- WAL 80
-
SMILESC1C2C3=CC=CC=C3CC4=CC=CC=C4N2C(=N1)N
-
InChIKeyWHWZLSFABNNENI-UHFFFAOYSA-N
- Pubchem - epinastine
- Wikipedia - epinastine
Epinastine (brand names Alesion, Elestat, Purivist, Relestat) is a second-generation antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis. It is produced by Allergan and marketed by Inspire in the United States. It is highly selective for the H1 receptor and does not cross the blood-brain-barrier.
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+
41218-84-2
(Imine formation from aldehyde)
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