| Weight | 285.778 g/mol |
|---|---|
| Formula | C16H16ClN3 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 0 |
Epinastine hydrochloride (108929-04-0)
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- Sigma-Aldrich - Epinastine hydrochloride118.00 - 456.00 USD
- Fisher Scientific - Search for Epinastine hydrochloride
- TCI - Epinastine hydrochloride136.00 - 794.00 USD
- Epinastine Hydrochloride Antagonism against Interleukin-4-Mediated T Cell Cytokine Imbalance in vitro (International Archives of Allergy and Immunology, 2006)
- Epinastine hydrochloride for atopic disease. (Drugs of Today, 2004)
- Suppressive activity of epinastine hydrochloride on TARC production from human peripheral blood CD4+ T cells invitro (Journal of Pharmacy and Pharmacology, 2005)
- Study of fluorescence interaction and conformational changes of bovine serum albumin with histamine H1-receptordrug epinastine hydrochloride by spectroscopic and time-resolved fluorescence methods (Biopolymers, 2015)
- Efficacy of epinastine hydrochloride ophthalmic solution in allergic conjunctivitis by conjunctival cedar pollen allergen challenge (Annals of Allergy Asthma & Immunology, 2014)
- Antiallergic drugs, azelastine hydrochloride and epinastine hydrochloride, inhibit ongoing IgE secretion of rat IgE-producing hybridoma FE-3 cells (European Journal of Pharmacology, 2006)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1C2C3=CC=CC=C3CC4=CC=CC=C4N2C(=N1)N.Cl
-
InChIKeyVKXSGUIOOQPGAF-UHFFFAOYSA-N
- Pubchem - Epinastine hydrochloride
- Wikipedia - epinastine hydrochloride
Epinastine (brand names Alesion, Elestat, Purivist, Relestat) is a second-generation antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis. It is produced by Allergan and marketed by Inspire in the United States. It is highly selective for the H1 receptor and does not cross the blood-brain-barrier.
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Synthesis
Reactant
+
41218-84-2
(Imine formation from aldehyde)
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Epinastine hydrochloride
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