| Weight | 351.921 g/mol |
|---|---|
| Formula | C23H26ClN |
| Hydrogen Acceptors | 1 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 7 |
Fendiline hydrochloride (13636-18-5)
Sensit · Fendiline · Fendilin
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- Fendiline inhibits K-Ras plasma membrane localization and blocks K-Ras signal transmission. (Molecular and Cellular Biology, 2013)
- Fendiline: a review of its basic pharmacological and clinical properties. (1987)
- Open State Block by Fendiline of L-Type Ca++ Channels in Ventricular Myocytes from Rat Heart (Journal of Pharmacology and Experimental Therapeutics, 1998)
- Fendiline increases [Ca2+]i in Madin Darby canine kidney (MDCK) cells by releasing internal Ca2+ followed by capacitative Ca2+ entry. (Life Sciences, 2000)
- Fendiline and calmidazolium enhance the release of endothelium-derived relaxant factor and of prostacyclin from cultured endothelial cells (Naunyn-schmiedebergs Archives of Pharmacology, 1988)
- Fendiline-evoked [Ca2+]i rises and non-Ca2+-triggered cell death in human oral cancer cells. (Human & Experimental Toxicology, 2009)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Sensit
- Fendiline
- Fendilin
- Senzit
-
SMILESCC(C1=CC=CC=C1)NCCC(C2=CC=CC=C2)C3=CC=CC=C3.Cl
-
InChIKeyNJXWZWXCHBNOOG-UHFFFAOYSA-N
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Synthesis
Reactant
+
1-Phenylethanamine
(Reductive amination)
benzene
+
Reactant
(Friedel-Crafts alkylation)
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