| Weight | 458.551 g/mol |
|---|---|
| Formula | C26H34O7 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 10 |
fumagillin (23110-15-8)
Score:
#645 in Microbiology
,
#2867 in Biochemistry
,
#5323 in Biology
,
#7018 in Chemistry
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- Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth (Nature, 1990)
- The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2 (Proceedings of the National Academy of Sciences of the United States of America, 1997)
- Structure of human methionine aminopeptidase-2 complexed with fumagillin. (Science, 1998)
- Endothelial 3 IntegrinTargeted Fumagillin Nanoparticles Inhibit Angiogenesis in Atherosclerosis (Arteriosclerosis, Thrombosis, and Vascular Biology, 2006)
- Potent anti-angiogenic action of AGM-1470: comparison to the fumagillin parent (Biochemical and Biophysical Research Communications, 1991)
- Total synthesis of (+-)-fumagillin (Journal of the American Chemical Society, 1972)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(=CCC1C(O1)(C)C2C(C(CCC23CO3)OC(=O)C=CC=CC=CC=CC(=O)O)OC)C
-
InChIKeyNGGMYCMLYOUNGM-UHFFFAOYSA-N
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