| Weight | 111.104 g/mol |
|---|---|
| Formula | C4H5N3O |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 0 |
Imexon (59643-91-3)
4-imino-1,3-diazabicyclo(3.1.0)hexan-2-one · BM-06002 · BM 06002
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LabBot
- Induction of mitochondrial changes in myeloma cells by imexon. (Blood, 2001)
- Induction of oxidative stress and apoptosis in myeloma cells by the aziridine-containing agent imexon (Biochemical Pharmacology, 2000)
- Chemical basis for the biological activity of imexon and related cyanoaziridines. (Journal of Medicinal Chemistry, 2004)
- Phase I Trial of Imexon in Patients With Advanced Malignancy (Journal of Clinical Oncology, 2007)
- Imexon-Induced Apoptosis in Multiple Myeloma Tumor Cells is Caspase-8 Dependent (Clinical Cancer Research, 2004)
- Molecular and cellular characterization of imexon-resistant RPMI8226/I myeloma cells. (Molecular Cancer Therapeutics, 2002)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 4-imino-1,3-diazabicyclo(3.1.0)hexan-2-one
- BM-06002
- BM 06002
-
SMILESC1C2N1C(=O)N=C2N
-
InChIKeyBIXBBIPTYBJTRY-UHFFFAOYSA-N
- Pubchem - Imexon
- Wikipedia - imexon
Imexon (INN, trade name Amplimexon) is a substance that is being studied in the treatment of some types of cancer, including pancreatic, lung, breast, prostate, melanoma, and multiple myeloma. It is a cyanoaziridine derivative.
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