| Weight | 416.135 g/mol |
|---|---|
| Formula | C18H14Cl4N2O |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 6 |
Isoconazole (27523-40-6)
Icaden · isoconazole nitrate · Gyno Icaden
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- Antifungal relative inhibition factors: BAY 19139, bifonazole, butoconazole, isoconazole, itraconazole (R 51211), oxiconazole, Ro 144767/002, sulconazole, terconazole and vibunazole (BAY n-7133) compared in vitro with nine established antifungal agents (Journal of Antimicrobial Chemotherapy, 1984)
- [Microbiological studies on isoconazole nitrate, a broad spectrum antimycotic from the series of imidazole derivatives (author's transl)]. (Drug Research, 1979)
- Non-invasive analysis of penetration and storage of Isoconazole nitrate in the stratum corneum and the hair follicles (European Journal of Pharmaceutics and Biopharmaceutics, 2012)
- Isoconazole nitrate in the treatment of tropical dermatomycoses. (Mycoses, 1994)
- Isoconazole nitrate versus clotrimazole in foot and nail infections due to Hendersonula toruloidea, Scytalidium hyalinum and dermatophytes (Mycoses, 2009)
- Contact dermatitis to isoconazole nitrate (Contact Dermatitis, 1983)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Icaden
- isoconazole nitrate
- Gyno Icaden
- R15454
- Gyno-Travogen
- Travogyn
- 1-(2,4-dichloro beta-(2,6-dichlorobenzyloxy)phenethyl) imidazole
- Fazol
-
SMILESC1=CC(=C(C(=C1)Cl)COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)Cl
-
InChIKeyMPIPASJGOJYODL-UHFFFAOYSA-N
- Pubchem - Isoconazole
- Wikipedia - isoconazole
Isoconazole is an azole antifungal drug and could inhibit gram positive bacteria. Nigerian and British medical researchers found that for foot and vaginal infections, isoconazole has a similar effectiveness to clotrimazole. Isoconazole nitrate may be used in combination with corticosteroid diflucortolone to increase its bioavailability.
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