| Weight | 448.595 g/mol |
|---|---|
| Formula | C25H28N2O4Si |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 4 |
Karenitecin (203923-89-1)
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- Potentiation of a Topoisomerase I Inhibitor, Karenitecin, by the Histone Deacetylase Inhibitor Valproic Acid in Melanoma: Translational and Phase I/II Clinical Trial (Clinical Cancer Research, 2009)
- Phase II Trial of Karenitecin in Patients with Malignant Melanoma: Clinical and Translational Study (Clinical Cancer Research, 2005)
- Phase I and pharmacokinetic study of karenitecin in patients with recurrent malignant gliomas. (Neuro-oncology, 2008)
- Preclinical and clinical activity of the topoisomerase I inhibitor, karenitecin, in melanoma. (Expert Opinion on Investigational Drugs, 2011)
- Phase II multicenter open-label study of karenitecin in previously treated epithelial ovarian and primary peritoneal cancer: a Gynecologic Oncology Group Study (International Journal of Gynecological Cancer, 2008)
- Phase II trial of karenitecin in patients with relapsed or refractory non-small cell lung cancer (CALGB 30004) (Lung Cancer, 2005)
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Predict GHS Hazards for Any Chemical in silico.
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SMILESCCC1(C2=C(COC1=O)C(=O)N3CC4=C(C5=CC=CC=C5N=C4C3=C2)CC[Si](C)(C)C)O
-
InChIKeyPOADTFBBIXOWFJ-UHFFFAOYSA-N
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