| Weight | 311.637 g/mol |
|---|---|
| Formula | C11H6ClN3O6 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 2 |
Lodoxamide (63610-09-3, 53882-12-5)
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- Efficacy and Safety of Lodoxamide 0.1% vs Cromolyn Sodium 4% in Patients with Vernal Keratoconjunctivitis (American Journal of Ophthalmology, 1992)
- Effect of lodoxamide and disodium cromoglycate on tear eosinophil cationic protein in vernal keratoconjunctivitis. (British Journal of Ophthalmology, 1997)
- Effects of lodoxamide on ischemic reperfused myocardium (Journal of Cardiovascular Pharmacology, 1982)
- Efficacy of Lodoxamide 0.1% Ophthalmic Solution in Resolving Corneal Epitheliopathy Associated With Vernal Keratoconjunctivitis (American Journal of Ophthalmology, 1994)
- Efficacy of lodoxamide eye drops on mast cells and eosinophils after allergen challenge in allergic conjunctivitis. (Ophthalmology, 1997)
- Mechanisms and comparison of anti-allergic efficacy of topical lodoxamide and cromolyn sodium treatment in vernal keratoconjunctivitis (Ophthalmology, 2000)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1=C(C=C(C(=C1NC(=O)C(=O)O)Cl)NC(=O)C(=O)O)C#N
-
InChIKeyRVGLGHVJXCETIO-UHFFFAOYSA-N
- Pubchem - Lodoxamide
- Wikipedia - lodoxamide
Lodoxamide is an antiallergic pharmaceutical drug. It is marketed under the tradename Alomide in the UK. Like cromoglicic acid it acts as a mast cell stabilizer.
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Synthesis
Reactant
+
dimethyl sulfide
(Corey-Kim oxidation of secondary alcohols)
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