| Weight | 429.557 g/mol |
|---|---|
| Formula | C25H35NO5 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 13 |
mebeverine (3625-06-7)
4-(ethyl-(4-methoxy-alpha-methylphenethyl)aminobutyl) veratrate · mebeverine hydrochloride · spasmotalin
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- Alosetron relieves pain and improves bowel function compared with mebeverine in female nonconstipated irritable bowel syndrome patients (Alimentary Pharmacology & Therapeutics, 1999)
- Comparison of the therapeutic effect of wheat bran, mebeverine and placebo in patients with the irritable bowel syndrome. (Digestion, 1986)
- Physiological and clinical assessment of the effect of the musculotropic agent mebeverine on the human colon. (BMJ, 1965)
- Application of first-derivative UV-spectrophotometry, TLC-densitometry and liquid chromatography for the simultaneous determination of mebeverine hydrochloride and sulpiride (Journal of Pharmaceutical and Biomedical Analysis, 1999)
- DEVELOPMENT OF IN SITU GELLING AND MUCOADHESIVE MEBEVERINE HYDROCHLORIDE SOLUTION FOR RECTAL ADMINISTRATION (2003)
- A systematic review of efficacy and tolerability of mebeverine in irritable bowel syndrome (World Journal of Gastroenterology, 2010)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - 4-(ethyl-(4-methoxy-alpha-methylphenethyl)aminobutyl) veratrate
- mebeverine hydrochloride
- spasmotalin
- duspatalin
-
SMILESCCN(CCCCOC(=O)C1=CC(=C(C=C1)OC)OC)C(C)CC2=CC=C(C=C2)OC
-
InChIKeyVYVKHNNGDFVQGA-UHFFFAOYSA-N
- Pubchem - mebeverine
- Wikipedia - mebeverine
Mebeverine is a drug used to alleviate some of the symptoms of irritable bowel syndrome. It works by relaxing the muscles in and around the gut.
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Synthesis
3,4-Dimethoxybenzoic acid
+
Reactant
(Ester from carboxilic acid(SN2))
ANISOLE
+
Reactant
(Friedel-Crafts alkylation)
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