| Weight | 216.192 g/mol |
|---|---|
| Formula | C12H8O4 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 1 |
methoxsalen (298-81-7)
Xanthotoxin · Oxsoralen · 8MOP
Score:
#121 in Biochemistry
,
#533 in Biology
,
#566 in Chemistry
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- Photochemotherapy of psoriasis with oral methoxsalen and longwave ultraviolet light. (The New England Journal of Medicine, 1974)
- Malignant Melanoma in Patients Treated for Psoriasis with Methoxsalen (Psoralen) and Ultraviolet A Radiation (PUVA) (The New England Journal of Medicine, 1997)
- Risk of Cutaneous Carcinoma in Patients Treated with Oral Methoxsalen Photochemotherapy for Psoriasis (The New England Journal of Medicine, 1979)
- Oral Methoxsalen Photochemotherapy for the Treatment of Psoriasis: A Cooperative Clinical Trial* (Journal of Investigative Dermatology, 1977)
- Oral methoxsalen photochemotherapy of mycosis fungoides. (Cancer, 1976)
- Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen (Nature Structural & Molecular Biology, 2005)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H302: Harmful if swallowed
Warning Acute toxicity, oral - Category 4 - H350: May cause cancer
Danger Carcinogenicity - Category 1A, 1B - H373: Causes damage to organs through prolonged or repeated exposure
Warning Specific target organ toxicity, repeated exposure - Category 2 - Xanthotoxin
- Oxsoralen
- 8MOP
- Meloxine
- Oxsoralen Ultra
- 8 MOP
- ICN Brand 2 of Methoxsalen
- Sanofi Synthelabo Brand of Methoxsalen
- Deltasoralen
- Methoxsalen Mex-America Brand
- Dermatech Brand of Methoxsalen
- Dermox
- Chinoin Brand of Methoxsalen
- Methoxsalen Canderm Brand
- DB Brand of Methoxsalen
- Ultramop
- Ammoidin
- ICN Brand 1 of Methoxsalen
- Puvalen
- Methoxsalen Delta Brand
- Canderm Brand of Methoxsalen
- Mladinine
- Methoxsalen Dermatech Brand
- Methoxsalen Sanofi-Synthelabo Brand
- Oxsoralen-Ultra
- ICN Brand 3 of Methoxsalen
- Geroxalen
- 8-MOP
- Methoxa-Dome
- Boehringer Ingelheim Brand of Methoxsalen
- Methoxa Dome
- 8 Methoxypsoralen
- Delta Brand of Methoxsalen
- Sanofi-Synthelabo Brand of Methoxsalen
- 8-Methoxypsoralen
- Mex America Brand of Methoxsalen
- Methoxsalen Chinoin Brand
- Mex-America Brand of Methoxsalen
- Meladinine
- Galderma Brand of Methoxsalen
- Meladinina
-
SMILESCOC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2
-
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- Pubchem - methoxsalen
- Wikipedia - methoxsalen
Methoxsalen (also called xanthotoxin, marketed under the trade names Oxsoralen, Deltasoralen, Meladinine) is a drug used to treat psoriasis, eczema, vitiligo, and some cutaneous lymphomas in conjunction with exposing the skin to UVA light from lamps or sunlight. Methoxsalen modifies the way skin cells receive the UVA radiation, allegedly clearing up the disease. The dosage comes in 10mg tablets, which are taken in the amount of 30mg 75minutes before a PUVA (psoralen + UVA) light treatment.
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methoxsalen
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