| Weight | 539.592 g/mol |
|---|---|
| Formula | C21H25N5O8S2 |
| Hydrogen Acceptors | 8 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 6 |
MEZLOCILLIN (51481-65-3, 59798-30-0)
Mezlin · Mezlocillin Sodium · Bay f 1353
Score:
#366 in Microbiology
,
#2908 in Biology
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- Effects of Prophylactic Antibiotic Therapy With Mezlocillin Plus Sulbactam on the Incidence and Height of Fever After Severe Acute Ischemic Stroke The Mannheim Infection in Stroke Study (MISS) (Stroke, 2008)
- Quality control limits for ampicillin, carbenicillin, mezlocillin, and piperacillin disk diffusion susceptibility tests: a collaborative study. (Journal of Clinical Microbiology, 1981)
- Azlocillin and Mezlocillin: New Ureido Penicillins (Antimicrobial Agents and Chemotherapy, 1978)
- Azlocillin, mezlocillin, and piperacillin: new broad-spectrum penicillins. (Annals of Internal Medicine, 1982)
- A Prospective Randomized Trial of Ceftazidime Versus Netilmicin Plus Mezlocillin in the Empirical Therapy of Presumed Sepsis in Cirrhotic Patients (Hepatology, 1997)
- A Randomized Study of Tobramycin Plus Ticarcillin, Tobramycin Plus Cephalothin and Ticarcillin, or Tobramycin Plus Mezlocillin in the Treatment of Infection in Neutropenic Patients with Malignancies (The American Journal of the Medical Sciences, 1984)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Mezlin
- Mezlocillin Sodium
- Bay f 1353
- Melocin
- Baypen
- Bayf 1353
- Mezlocilline
- Meslocillin
- Bay-f 1353
- curasan Brand of Mezlocillin Sodium (Sterile)
- Bayer Brand of Mezlocillin Sodium (Sterile)
-
SMILESCC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)NC(=O)N4CCN(C4=O)S(=O)(=O)C)C(=O)O)C
-
InChIKeyYPBATNHYBCGSSN-UHFFFAOYSA-N
- Pubchem - MEZLOCILLIN
- Wikipedia - mezlocillin
Mezlocillin is a broad-spectrum penicillin antibiotic. It is active against both Gram-negative and some Gram-positive bacteria. Unlike most other extended spectrum penicillins, it is excreted by the liver, therefore it is useful for biliary tract infections, such as ascending cholangitis.
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Synthesis
Reactant
+
6-Aminopenicillanic acid
(Schotten-Baumann amide from acid)
benzene
+
Reactant
(Friedel-Crafts alkylation)
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MEZLOCILLIN
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