| Weight | 498.576 g/mol |
|---|---|
| Formula | C27H34N2O7 |
| Hydrogen Acceptors | 7 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 11 |
MOEXIPRIL (109715-88-0, 103775-10-6)
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- Drug-Excipient Incompatibility Studies of the Dipeptide Angiotensin-Converting Enzyme Inhibitor, Moexipril Hydrochloride: Dry Powder vs Wet Granulation (Pharmaceutical Research, 1990)
- Enalapril and moexipril protect from free radical-induced neuronal damage in vitro and reduce ischemic brain injury in mice and rats (European Journal of Pharmacology, 1999)
- Impact of antihypertensive therapy on postmenopausal osteoporosis: effects of the angiotensin converting enzyme inhibitor moexipril, 17beta-estradiol and their combination on the ovariectomy-induced cancellous bone loss in young rats. (Journal of Hypertension, 1995)
- An Unexpected pH Effect on the Stability of Moexipril Lyophilized Powder (Pharmaceutical Research, 1989)
- Simultaneous determination of moexipril hydrochloride and hydrochlorothiazide in tablets by derivative spectrophotometric and high-performance liquid chromatographic methods. (Journal of Pharmaceutical and Biomedical Analysis, 2003)
- Moexipril, a new angiotensin-converting enzyme (ACE) inhibitor: pharmacological characterization and comparison with enalapril. (Journal of Pharmacology and Experimental Therapeutics, 1995)
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SMILESCCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3=CC(=C(C=C3CC2C(=O)O)OC)OC
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- Pubchem - MOEXIPRIL
- Wikipedia - moexipril
Moexipril hydrochloride is a potent orally active nonsulfhydryl angiotensin converting enzyme inhibitor (ACE inhibitor) which is used for the treatment of hypertension and congestive heart failure. Moexipril can be administered alone or with other antihypertensives or diuretics. It works by inhibiting the conversion of angiotensin I to angiotensin II.
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Reactant
+
103733-66-0
(Schotten-Baumann amide from acid)
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