neostigmine bromide (114-80-7)

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Suppliers

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  5 mg
  $45.00

  10 mg
  $55.00

  25 mg
  $75.00

  1 g
  $100.00

  5 g
  $190.00

Most-cited Publications

• Neostigmine for the treatment of acute colonic pseudo-obstruction. (The New England Journal of Medicine, 1999)
• Letter: Experimental myopathy induced by neostigmine methylsulphate. (The Lancet, 1975)
• Phase I safety assessment of intrathecal neostigmine methylsulfate in humans (Anesthesiology, 1995)
• Reversal of profound rocuronium-induced blockade with sugammadex: a randomized comparison with neostigmine. (Anesthesiology, 2008)
• Microinjection of neostigmine into the pontine reticular formation of cats enhances desynchronized sleep signs. (Journal of Pharmacology and Experimental Therapeutics, 1984)
• NERVE ACTIVITY ACCOMPANYING FASCICULATION PRODUCED BY PROSTIGMIN (Journal of Neurophysiology, 1940)

Areas of Application

Safety

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Trends

Alternate Names

• Neostigmine
• Prostigmin
• Prostigmine
• Neostigmine Methylsulfate
• Syntostigmine
• Synstigmin
• Proserine
• Polstigmine
• Prozerin
• SMILES
  CN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C.[Br-]
• InChIKey
  LULNWZDBKTWDGK-UHFFFAOYSA-M

External Links

• Pubchem - neostigmine bromide
• Wikipedia - neostigmine bromide
  Neostigmine, sold under the brand name Prostigmin among others, is a medication used to treat myasthenia gravis, Ogilvie syndrome, and urinary retention without the presence of a blockage. It is also used together with atropine to end the effects of neuromuscular blocking medication of the non-depolarizing type. It is given by injection either into a vein, muscle, or under the skin.

Synthesis

Methylboronic acid  +  17752-10-2 (Chan-Lam coupling reaction)

Synthesis of neostigmine bromide ›

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