| Weight | 288.212 g/mol |
|---|---|
| Formula | C10H12N2O8 |
| Hydrogen Acceptors | 8 |
| Hydrogen Donors | 5 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 3 |
Orotidine (314-50-1)
Score:
#2136 in Biochemistry
,
#4385 in Biology
,
#5543 in Chemistry
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- A positive selection for mutants lacking orotidine-5-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance (Molecular Genetics and Genomics, 1984)
- Isolation of the Candida albicans gene for orotidine-5'-phosphate decarboxylase by complementation of S. cerevisiae ura3 and E. coli pyrF mutations (Molecular Genetics and Genomics, 1984)
- Transformation of Aspergillus nidulans by the orotidine-5-phosphate decarboxylase gene of Neurospora crassa (Biochemical and Biophysical Research Communications, 1983)
- Enzymatic synthesis of pyrimidine nucleotides; orotidine-5'-phosphate and uridine-5'-phosphate. (Journal of Biological Chemistry, 1955)
- Development of a homologous transformation system for the human pathogenic fungus Aspergillus fumigatus based on the pyrG gene encoding orotidine 5-monophosphate decarboxylase (Current Genetics, 1998)
- Electrostatic stress in catalysis: Structure and mechanism of the enzyme orotidine monophosphate decarboxylase (Proceedings of the National Academy of Sciences of the United States of America, 2000)
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Predict GHS Hazards for Any Chemical in silico.
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SMILESC1=C(N(C(=O)NC1=O)C2C(C(C(O2)CO)O)O)C(=O)O
-
InChIKeyFKCRAVPPBFWEJD-UHFFFAOYSA-N
- Pubchem - Orotidine
- Wikipedia - orotidine
Orotidine is a nucleoside formed by attaching orotic acid to a ribose ring via a -N1-glycosidic bond. It is found in bacteria, fungi and plants. It was first isolated in 1951 from the fungus Neurospora by A.
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