Score: #485 in Neuroscience , #2230 in Biology

  Antiarrhythmic agent · Antipsychotic · Aromatic compound · Chemical classes of psychoactive drug · Cyclic compound · D2 antagonist · D3 antagonist · D4 antagonist · Diphenylbutylpiperidine · Dopamine antagonist · Drugs acting on the cardiovascular system · Drugs acting on the nervous system · Fluoroarene · Organic compound · Pharmaceutical · Potassium channel blocker · Psychoactive drug · Psychoactive drugs by mechanism of action · Psychopharmacology · Typical antipsychotic · Urea

LabBot

Procurement
Synthesis
Safety
Alternatives
Testing
Regulation
Thanks, you'll receive a follow-up email shortly!

Suppliers

• Sigma-Aldrich - pimozide
  77.00 - 338.10 USD
• Fisher Scientific - Search for pimozide
• TCI - Search for pimozide

Most-cited Publications

• Neuroleptic-induced "anhedonia" in rats: pimozide blocks reward quality of food (Science, 1978)
• Increased lever pressing for amphetamine after pimozide in rats: implications for a dopamine theory of reward (Science, 1975)
• Blockade of cocaine reinforcement in rats with the dopamine receptor blocker pimozide, but not with the noradrenergic blockers phentolamine or phenoxybenzamine. (Canadian Journal of Psychology\/revue Canadienne De Psychologie, 1977)
• Pimozide-induced extinction of intracranial self-stimulation: response patterns rule out motor or performance deficits (Brain Research, 1976)
• Controlled Study of Haloperidol, Pimozide, and Placebo for the Treatment of Gilles de la Tourette's Syndrome (Archives of General Psychiatry, 1989)
• Pimozide blocks establishment but not expression of amphetamine-produced environment-specific conditioning. (Science, 1983)

Areas of Application

Safety

• Request a Demo
  Predict GHS Hazards for Any Chemical in silico.
  Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more.

Trends

Alternate Names

• Orap
• Antalon
• Orap forte
• R-6238
• R6238
• Pharmascience Brand of Pimozide
• Janssen Brand of Pimozide
• ASTA Medica Brand of Pimozide
• SMILES
  C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCCC(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F
• InChIKey
  YVUQSNJEYSNKRX-UHFFFAOYSA-N

External Links

• Pubchem - pimozide
• Wikipedia - pimozide
  Pimozide (sold under the brand name Orap) is an antipsychotic drug of the diphenylbutylpiperidine class. It was discovered at Janssen Pharmaceutica in 1963. It has a high potency compared to chlorpromazine (ratio 50-70:1).

Similar Compounds

• Account Setup
• Social Profiles
• Personal Details

Which industry is this for?

• Research
• Manufacturing
• CRO / CMO
• Pharmaceuticals
• Government / Regulation
• Services

What is your zip code / postal code?

We'll find the best matches for your location.

Finding the Best Matches

Where should we send your matches?