| Weight | 438.524 g/mol |
|---|---|
| Formula | C25H30N2O5 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 9 |
quinapril (85441-61-8)
Score:
#953 in Biochemistry
,
#2518 in Biology
,
#3142 in Chemistry
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- Angiotensin-Converting Enzyme Inhibition With Quinapril Improves Endothelial Vasomotor Dysfunction in Patients With Coronary Artery Disease (Circulation, 1996)
- Angiotensin-Converting Enzyme Inhibition With Quinapril Improves Endothelial Vasomotor Dysfunction in Patients With Coronary Artery Disease The TREND (Trial on Reversing ENdothelial Dysfunction) Study (Circulation, 1996)
- The Quinapril Ischemic Event Trial (QUIET): evaluation of chronic ace inhibitor therapy in patients with ischemic heart disease and preserved left ventricular function (American Journal of Cardiology, 2001)
- Effects of Quinapril on Clinical Outcome After Coronary Artery Bypass Grafting (The QUO VADIS Study) (American Journal of Cardiology, 2001)
- ACE Inhibitor Quinapril Reduces the Arterial Expression of NF-B-Dependent Proinflammatory Factors but not of Collagen I in a Rabbit Model of Atherosclerosis (American Journal of Pathology, 1998)
- The Clinical Pharmacokinetics of Quinapril (Angiology, 1989)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3=CC=CC=C3CC2C(=O)O
-
InChIKeyJSDRRTOADPPCHY-UHFFFAOYSA-N
- Pubchem - quinapril
- Wikipedia - quinapril
Quinapril (marketed under the brand name Accupril by Pfizer) is an angiotensin-converting enzyme inhibitor (ACE inhibitor) used in the treatment of hypertension and congestive heart failure. A prodrug, it is converted to its active metabolite, quinaprilat, in the liver.
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Reactant
+
1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
(Schotten-Baumann amide from acid)
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