| Weight | 328.496 g/mol |
|---|---|
| Formula | C22H32O2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 6 |
RETINYL ACETATE
vitamin A acetate · retinol acetate · Dagravit A Forte
127-47-9, 64536-04-5, 34356-31-5
Score:
#1498 in Biochemistry
,
#4394 in Chemistry
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- Altered differentiation of mouse epidermal cells treated with retinyl acetate in vitro (Experimental Cell Research, 1974)
- Concurrent liquid-chromatographic assay of retinol, alpha-tocopherol, beta-carotene, alpha-carotene, lycopene, and beta-cryptoxanthin in plasma, with tocopherol acetate as internal standard. (Clinical Chemistry, 1988)
- Inhibitory effects of retinoic acid or retinyl acetate on the growth of untransformed, transformed, and tumor cells in vitro. (Journal of the National Cancer Institute, 1977)
- Retinyl acetate inhibits mammary carcinogenesis induced by N-methyl-N-nitrosourea (Nature, 1977)
- Inhibition of 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis by retinyl acetate. (Cancer Research, 1976)
- Modulation of Involucrin and Envelope Competence in Human Keratinocytes by Hydrocortisone, Retinyl Acetate, and Growth Arrest (Cancer Research, 1983)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - vitamin A acetate
- retinol acetate
- Dagravit A Forte
- Vitamin-A-Saar
- Vitamin A Dispersa
- Dif Vitamin A Masivo
- retinol acetate, (9,13-cis)-isomer
- 9-cis-retinyl acetate
- all-trans-retinyl acetate
- QLT091001
- RetiNit
-
SMILESCC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CCOC(=O)C)C)C
-
InChIKeyQGNJRVVDBSJHIZ-UHFFFAOYSA-N
- Pubchem - RETINYL ACETATE
- Wikipedia - vitamin a acetate
Retinyl acetate (retinol acetate, vitamin A acetate) is a natural form of vitamin A which is the acetate ester of retinol. It has potential antineoplastic and chemopreventive activities. In the United States, retinyl acetate is classified generally recognized as safe (GRAS) in the amounts used to fortify foods with vitamin A.
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Synthesis
(E)-3-Formylbut-2-enyl acetate
+
Reactant
(Wittig)
1,3,3-Trimethylcyclohexene
+
Reactant
(Heck non-terminal vinyl)
Acetic Acid
+
Reactant
(Ester from carboxilic acid(SN2))
Reactant
+
dimethyl sulfide
(Corey-Kim oxidation of secondary alcohols)
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RETINYL ACETATE
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