| Weight | 274.408 g/mol |
|---|---|
| Formula | C17H26N2O |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 4 |
Ropivacaine (98717-15-8, 84057-95-4)
Score:
#836 in Biochemistry
,
#2245 in Biology
,
#2764 in Chemistry
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- Central nervous and cardiovascular effects of i.v. infusions of ropivacaine, bupivacaine and placebo in volunteers. (BJA: British Journal of Anaesthesia, 1997)
- Acute Toxicity of Ropivacaine Compared with That of Bupivacaine (Anesthesia & Analgesia, 1989)
- Successful resuscitation of a patient with ropivacaine-induced asystole after axillary plexus block using lipid infusion* (Anaesthesia, 2006)
- Relative Analgesic Potencies of Ropivacaine and Bupivacaine for Epidural Analgesia in Labor Implications for Therapeutic Indexes (Anesthesiology, 1999)
- Comparative systemic toxicity of convulsant and supraconvulsant doses of intravenous ropivacaine, bupivacaine, and lidocaine in the conscious dog. (Anesthesia & Analgesia, 1989)
- Cardiac resuscitation after incremental overdosage with lidocaine, bupivacaine, levobupivacaine, and ropivacaine in anesthetized dogs (Anesthesia & Analgesia, 2001)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C
-
InChIKeyZKMNUMMKYBVTFN-UHFFFAOYSA-N
- Pubchem - Ropivacaine
- Wikipedia - ropivacaine
Ropivacaine (rINN) is a local anaesthetic drug belonging to the amino amide group. The name ropivacaine refers to both the racemate and the marketed S-enantiomer. Ropivacaine hydrochloride is commonly marketed by AstraZeneca under the trade name Naropin.
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Synthesis
Reactant
+
2,6-Dimethylaniline
(Schotten-Baumann amide from acid)
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Ropivacaine
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