| Weight | 418.574 g/mol |
|---|---|
| Formula | C25H38O5 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 6 |
simvastatin (79902-63-9)
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- Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S) (The Lancet, 1994)
- MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial. (The Lancet, 2003)
- Simvastatin and Niacin, Antioxidant Vitamins, or the Combination for the Prevention of Coronary Disease (The New England Journal of Medicine, 2001)
- Cholesterol Lowering With Simvastatin Improves Prognosis of Diabetic Patients With Coronary Heart Disease: A subgroup analysis of the Scandinavian Simvastatin Survival Study (4S) (Diabetes Care, 1997)
- The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection) : a randomised placebo-controlled trial (The Lancet, 2011)
- The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals (Nature Medicine, 2000)
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Predict GHS Hazards for Any Chemical in silico.
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SMILESCCC(C)(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C
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InChIKeyRYMZZMVNJRMUDD-UHFFFAOYSA-N
- Pubchem - simvastatin
- Wikipedia - simvastatin
Simvastatin, marketed under the trade name Zocor among others, is a lipid-lowering medication. It is used along with exercise, diet, and weight loss to decrease elevated lipid (fat) levels. It is also used to decrease the risk of heart problems in those at high risk.
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simvastatin
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