Weight | 471.685 g/mol |
---|---|
Formula | C32H41NO2 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 2 |
Aromatic Rings | 3 |
Rotatable Bonds | 8 |
terfenadine (50679-08-8)
Seldane · Terfenidine · Sigma Tau Brand of Terfenadine
Score:
#190 in Neuroscience
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#228 in Biochemistry
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#895 in Biology
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#990 in Chemistry
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- Sigma-Aldrich - terfenadine80.60 - 338.10 USD
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- Terfenadine-ketoconazole interaction : pharmacokinetic and electrocardiographic consequences (JAMA, 1993)
- Torsades de pointes occurring in association with terfenadine use (JAMA, 1990)
- Mechanism of the Cardiotoxic Actions of Terfenadine (JAMA, 1993)
- Changes in the pharmacokinetics and electrocardiographic pharmacodynamics of terfenadine with concomitant administration of erythromycin (Clinical Pharmacology & Therapeutics, 1992)
- HERG, a Primary Human Ventricular Target of the Nonsedating Antihistamine Terfenadine (Circulation, 1996)
- Blockade of HERG channels expressed in Xenopus oocytes by the histamine receptor antagonists terfenadine and astemizole. (FEBS Letters, 1996)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Seldane
- Terfenidine
- Sigma Tau Brand of Terfenadine
- Cyater
- Stadapharm Brand of Terfenadine
- ratiopharm Brand of Terfenadine
- RMI 9918
- Ternadin
- RMI-9918
- Hisfedin
- Heumann Brand of Terfenadine
- Merck dura Brand of Terfenadine
- Terfenadin Stada
- RMI9918
- Terfenadin Heumann
- Wolff Brand of Terfenadine
- Terfedura
- Cantabria Brand of Terfenadine
- Dolorgiet Brand of Terfenadine
- Mundipharma Brand of Terfenadine
- Aliud Brand of Terfenadine
- Terfenadin-ratiopharm
- ct Arzneimittel Brand of Terfenadine
- ct-Arzneimittel Brand of Terfenadine
- Terfemundin
- alpha-(4-(1,1-Dimethylethyl)phenyl)-4-(hydroxydiphenylmethyl)-1-piperdinebutanol
- Balkis Saft Spezial
- Terfenadin AL
- Teldane
- terfenadin von ct
- Rapidal
- Sigma-Tau Brand of Terfenadine
- Bial Brand of Terfenadine
- Hoechst Brand of Terfenadine
- Triludan
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SMILESCC(C)(C)C1=CC=C(C=C1)C(CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)O
-
InChIKeyGUGOEEXESWIERI-UHFFFAOYSA-N
- Pubchem - terfenadine
- Wikipedia - terfenadine
Terfenadine is an antihistamine formerly used for the treatment of allergic conditions. It was brought to market by Hoechst Marion Roussel (now Sanofi-Aventis) and was marketed under various brand names, including Seldane in the United States, Triludan in the United Kingdom, and Teldane in Australia. It was superseded by fexofenadine in the 1990s due to the risk of a particular type of disruption of the electrical rhythms of the heart (specifically cardiac arrhythmia caused by QT interval prolongation) and has been withdrawn from markets worldwide.
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