| Weight | 369.425 g/mol |
|---|---|
| Formula | C19H23N5O3 |
| Hydrogen Acceptors | 8 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 6 |
trimetrexate (52128-35-5)
Score:
#286 in Microbiology
,
#944 in Biochemistry
,
#2500 in Biology
,
#3121 in Chemistry
"What do you need help with?"
LabBot
- Sigma-Aldrich - Search for trimetrexate
- Fisher Scientific - Search for trimetrexate
- TCI - Search for trimetrexate
- Trimetrexate for the Treatment of Pneumocystis carinii Pneumonia in Patients with the Acquired Immunodeficiency Syndrome (The New England Journal of Medicine, 1987)
- A gene transfer strategy for making bone marrow cells resistant to trimetrexate (Blood, 1996)
- Patterns of cross-resistance to the antifolate drugs trimetrexate, metoprine, homofolate, and CB3717 in human lymphoma and osteosarcoma cells resistant to methotrexate. (Cancer Research, 1983)
- Uptake and efficacy of trimetrexate (TMQ, 2,4-diamino-5-methyl-6-[(3,4,5-trimethoxyanilino)methyl] quinazoline), a non-classical antifolate in methotrexate-resistant leukemia cells in vitro (Biochemical Pharmacology, 1984)
- Biochemical pharmacology of the lipophilic antifolate, trimetrexate (Advances in Enzyme Regulation, 1984)
- Folate antagonists. 20. Synthesis and antitumor and antimalarial properties of trimetrexate and related 6-[(phenylamino)methyl]-2,4-quinazolinediamines (Journal of Medicinal Chemistry, 1983)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1=C(C=CC2=C1C(=NC(=N2)N)N)CNC3=CC(=C(C(=C3)OC)OC)OC
-
InChIKeyNOYPYLRCIDNJJB-UHFFFAOYSA-N
- Pubchem - trimetrexate
- Wikipedia - trimetrexate
Trimetrexate is a quinazoline derivative. It is a dihydrofolate reductase inhibitor.
Suppliers
Most-cited Publications
Areas of Application
Safety
Alternate Names
External Links
Similar Compounds
79-97-0
(79-97-0)
1 alternate name
3 suppliers
Tetrahydrocurcumin
(36062-04-1)
1 alternate name
3 suppliers
PAPAVERINE HYDROCHLORIDE
(61-25-6)
1 alternate name
3 suppliers
Dimethomorph
(110488-70-5)
1 alternate name
2 safety hazards
3 suppliers
54827-17-7
(54827-17-7)
1 alternate name
3 suppliers
Paroxetine hydrochloride
(78246-49-8, 110429-35-1)
1 alternate name
3 suppliers
Erlotinib hydrochloride
(183319-69-9)
1 alternate name
3 suppliers
Flutriafol
(76674-21-0)
1 alternate name
3 suppliers
ERIODICTYOL
(552-58-9, 4049-38-1)
1 alternate name
3 suppliers
Metconazole
(125116-23-6)
1 alternate name
3 safety hazards
3 suppliers
Fuchsine Base
(3248-93-9)
1 alternate name
3 suppliers
Cinacalcet hydrochloride
(364782-34-3)
1 alternate name
3 suppliers
Phenmedipham
(13684-63-4)
1 alternate name
3 safety hazards
3 suppliers
Oripavine
(467-04-9)
1 alternate name
3 suppliers
Sinoacutine
(4090-18-0)
1 alternate name
3 suppliers
Dobutamine hydrochloride
(49745-95-1)
1 alternate name
3 suppliers
retinal
(116-31-4)
1 alternate name
3 suppliers
9-cis-Retinal
(514-85-2)
1 alternate name
3 suppliers
Nobiletin
(478-01-3)
1 alternate name
3 suppliers
Pararosaniline base
(467-62-9)
1 alternate name
3 suppliers
3,3',4,4',5,5'-Hexachlorobiphenyl
(1336-36-3, 32774-16-6)
1 alternate name
2 safety hazards
3 suppliers
p,p'-DDE
(68679-99-2, 72-55-9)
1 alternate name
3 suppliers
Tetrabromobisphenol A
(79-94-7)
1 alternate name
4 safety hazards
3 suppliers
AMITRAZ
(33089-61-1)
1 alternate name
5 safety hazards
3 suppliers
RACTOPAMINE
(97825-25-7)
1 alternate name
3 suppliers
Vidarabine monohydrate
(24356-66-9)
1 alternate name
3 suppliers
Prazosin hydrochloride
(19237-84-4)
1 alternate name
3 suppliers
Tetrachlorobisphenol A
(79-95-8)
1 alternate name
3 suppliers
Tribromobisphenol A
(6386-73-8)
1 alternate name
3 suppliers
Basic violet 14
(58969-01-0, 632-99-5)
1 alternate name
1 safety hazard
3 suppliers
Lucidin
(478-08-0)
1 alternate name
3 suppliers
Fenoterol hydrobromide
(1944-12-3, 13392-18-2)
1 alternate name
3 suppliers
NONIVAMIDE
(2444-46-4)
1 alternate name
3 suppliers
Terazosin hydrochloride
(63074-08-8)
1 alternate name
3 suppliers
2,7-DIMETHYLPYRENE
(15679-24-0)
1 alternate name
3 suppliers
Isorhamnetin
(480-19-3)
1 alternate name
3 suppliers
Dihydrocapsaicin
(19408-84-5)
1 alternate name
3 suppliers
CAS Directory
