| Weight | 610.751 g/mol |
|---|---|
| Formula | C37H42N2O6+2 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 4 |
| Rotatable Bonds | 2 |
Tubocurarine,d (6989-98-6)
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- Simultaneous modeling of pharmacokinetics and pharmacodynamics: application to d-tubocurarine. (Clinical Pharmacology & Therapeutics, 1979)
- Determinants of Apamin and d-Tubocurarine Block in SK Potassium Channels (Journal of Biological Chemistry, 1997)
- d-Tubocurarine binding sites are located at alpha-gamma and alpha-delta subunit interfaces of the nicotinic acetylcholine receptor (Proceedings of the National Academy of Sciences of the United States of America, 1990)
- The action of d-tubocurarine and of decamethonium on respiratory and other muscles in the cat. (The Journal of Physiology, 1951)
- Neuromuscular transmission in a mammalian preparation in the absence of blocking drugs and the effect of D-tubocurarine. (The Journal of Physiology, 1973)
- Neuromuscular Effects of d-Tubocurarine, Edrophonium and Neostigmine in Man (Anesthesiology, 1967)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC[NH+]1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C6C(CC7=CC(=C(C=C7)O)O3)[N+](CCC6=CC(=C5O)OC)(C)C)OC
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InChIKeyJFJZZMVDLULRGK-UHFFFAOYSA-P
- Pubchem - Tubocurarine,d
- Wikipedia - tubocurarine chloride
Tubocurarine (also known as d-tubocurarine or DTC) is a toxic alkaloid historically known for its use as an arrow poison. In the mid-1900s, it was used in conjunction with an anesthetic to provide skeletal muscle relaxation during surgery or mechanical ventilation. It is now rarely used as an adjunct for clinical anesthesia because safer alternatives, such as cisatracurium and rocuronium, are available.
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