| Weight | 288.387 g/mol |
|---|---|
| Formula | C18H24O3 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 0 |
2-Hydroxyestradiol (362-05-0)
Score:
#1393 in Biochemistry
,
#3340 in Biology
,
#4163 in Chemistry
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- Antioxidant effects of estradiol and 2-hydroxyestradiol on iron-induced lipid peroxidation of rat liver microsomes. (Steroids, 1994)
- Estradiol and its metabolites 4-hydroxyestradiol and 2-hydroxyestradiol induce mutations in human breast epithelial cells (International Journal of Cancer, 2006)
- Inhibition of Catechol O-Methyltransferase-catalyzed O-Methylation of 2- and 4-Hydroxyestradiol by Quercetin POSSIBLE ROLE IN ESTRADIOL-INDUCED TUMORIGENESIS (Journal of Biological Chemistry, 1996)
- 2-Hydroxyestradiol interaction with dopamine receptor binding in rat anterior pituitary. (Journal of Biological Chemistry, 1979)
- Mutagenic activity of 4-hydroxyestradiol, but not 2-hydroxyestradiol, in BB rat2 embryonic cells, and the mutational spectrum of 4-hydroxyestradiol (Chemical Research in Toxicology, 2006)
- Binding of 2-hydroxyestradiol and 4-hydroxyestradiol to estrogen receptors from human breast cancers (Journal of Steroid Biochemistry, 1989)
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SMILESCC12CCC3C(C1CCC2O)CCC4=CC(=C(C=C34)O)O
-
InChIKeyDILDHNKDVHLEQB-UHFFFAOYSA-N
- Pubchem - 2-Hydroxyestradiol
- Wikipedia - 2-hydroxyestradiol
2-Hydroxyestradiol (2-OHE2), also known as estra-1,3,5(10)-triene-2,3,17-triol, is an endogenous steroid, catechol estrogen, and metabolite of estradiol, as well as a positional isomer of estriol.
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