| Weight | 634.614 g/mol |
|---|---|
| Formula | C31H35N2NaO11 |
| Hydrogen Acceptors | 11 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 8 |
Albamycin (1476-53-5)
Novobiocin · Novobiocin Sodium · Streptonivicin
Score:
#340 in Microbiology
,
#1079 in Biochemistry
,
#2789 in Biology
,
#3495 in Chemistry
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Suppliers
- Sigma-Aldrich - Albamycin58.40 - 805.00 USD
- Fisher Scientific - Search for Albamycin
- TCI - Search for Albamycin
Most-cited Publications
- Novobiocin and coumermycin inhibit DNA supercoiling catalyzed by DNA gyrase (Proceedings of the National Academy of Sciences of the United States of America, 1976)
- The heat shock protein 90 antagonist novobiocin interacts with a previously unrecognized ATP-binding domain in the carboxyl terminus of the chaperone. (Journal of Biological Chemistry, 2000)
- Novobiocin and Related Coumarins and Depletion of Heat Shock Protein 90-Dependent Signaling Proteins (Journal of the National Cancer Institute, 2000)
- Energy coupling in DNA gyrase and the mechanism of action of novobiocin (Proceedings of the National Academy of Sciences of the United States of America, 1978)
- Novobiocin and additional inhibitors of the Hsp90 C-terminal nucleotide-binding pocket. (Current Medicinal Chemistry, 2008)
- The BaeSR Two-Component Regulatory System Activates Transcription of the yegMNOB (mdtABCD) Transporter Gene Cluster in Escherichia coli and Increases Its Resistance to Novobiocin and Deoxycholate (Journal of Bacteriology, 2002)
Areas of Application
Safety
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more.
Alternate Names
- Novobiocin
- Novobiocin Sodium
- Streptonivicin
- Monosodium Salt Novobiocin
- Crystallinic Acid
- Novobiocin Calcium
-
SMILESCC1=C(C=CC2=C1OC(=O)C(=C2[O-])NC(=O)C3=CC(=C(C=C3)O)CC=C(C)C)OC4C(C(C(C(O4)(C)C)OC)OC(=O)N)O.[Na+]
-
InChIKeyWWPRGAYLRGSOSU-UHFFFAOYSA-M
External Links
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