| Weight | 367.446 g/mol |
|---|---|
| Formula | C18H29N3O5 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 5 |
Bambuterol (81732-65-2, 81732-46-9)
Score:
#1309 in Biochemistry
,
#4008 in Chemistry
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- Bambuterol, a carbamate ester prodrug of terbutaline, as inhibitor of cholinesterases in human blood. (Drug Metabolism and Disposition, 1988)
- Determination of a basic drug, bambuterol, in human plasma by capillary electrophoresis using double stacking for large volume injection and supported liquid membranes for sample pretreatment. (Journal of Chromatography B: Biomedical Sciences and Applications, 1997)
- Hydrolysis of 3H-bambuterol, a carbamate prodrug of terbutaline, in blood from humans and laboratory animals in vitro (Biochemical Pharmacology, 1988)
- BLOOD EOSINOPHIL NUMBERS AND ACTIVITY DURING 24 HOURS - EFFECTS OF TREATMENT WITH BUDESONIDE AND BAMBUTEROL (The Journal of Allergy and Clinical Immunology, 1992)
- Quantification of bambuterol hydrochloride in a formulated product using solid-state NMR (Journal of Pharmaceutical and Biomedical Analysis, 2005)
- Bambuterol in the Treatment of Asthma: A Placebo-Controlled Comparison of Once-Daily Morning vs Evening Administration (Chest, 1995)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC(C)(C)NCC(C1=CC(=CC(=C1)OC(=O)N(C)C)OC(=O)N(C)C)O
-
InChIKeyANZXOIAKUNOVQU-UHFFFAOYSA-N
- Pubchem - Bambuterol
- Wikipedia - bambuterol
Bambuterol (INN) is a long-acting adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a prodrug of terbutaline. Commercially, the AstraZeneca pharmaceutical company produces and markets bambuterol as Bambec and Oxeol. It is not available in the U.S.
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Synthesis
tert-Butylamine
+
Reactant
(Alkylation of primary amines)
ODGNJEHRJKMKGI-UHFFFAOYSA-N
+
Reactant
(Friedel-Crafts alkylation)
Reactant
+
Dimethylamine
(Schotten-Baumann amide from acid)
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