Weight | 563.987 g/mol |
---|---|
Formula | C27H30ClNO10 |
Hydrogen Acceptors | 11 |
Hydrogen Donors | 5 |
Aromatic Rings | 2 |
Rotatable Bonds | 4 |
DAUNORUBICIN HYDROCHLORIDE (71214-33-0, 23541-50-6)
Daunorubicin · Daunomycin · Cerubidine
Score:
#1274 in Biochemistry
,
#3138 in Biology
,
#3926 in Chemistry
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- A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin (Biochemical Pharmacology, 1999)
- Studies on interaction of anthracycline antibiotics and deoxyribonucleic acid: equilibrium binding studies on the interaction of daunomycin with deoxyribonucleic acid (Biochemistry, 1982)
- Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals (Cell, 1995)
- Active outward transport of daunomycin in resistant Ehrlich ascites tumor cells. (Biochimica et Biophysica Acta, 1973)
- Generation of free radicals and lipid peroxidation by redox cycling of adriamycin and daunomycin (Biochemical and Biophysical Research Communications, 1977)
- High-dose daunorubicin in older patients with acute myeloid leukemia (The New England Journal of Medicine, 2009)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Daunorubicin
- Daunomycin
- Cerubidine
- Rubidomycin
- Daunoblastin
- NSC 82151
- Dauno Rubidomycine
- Dauno-Rubidomycine
- Daunoblastine
- NSC-82151
- NSC82151
- Rubomycin
-
SMILESCC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)C)O)N)O.Cl
-
InChIKeyGUGHGUXZJWAIAS-UHFFFAOYSA-N
- Pubchem - DAUNORUBICIN HYDROCHLORIDE
- Wikipedia - daunorubicin hydrochloride
Daunorubicin, also known as daunomycin, is a chemotherapy medication used to treat cancer. Specifically it is used for acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), chronic myelogenous leukemia (CML), and Kaposi's sarcoma. It is used by injection into a vein.
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