| Weight | 386.576 g/mol |
|---|---|
| Formula | C25H38O3 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 7 |
Dexanabinol (112924-45-5)
Score:
#828 in Neuroscience
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#3640 in Biology
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#4567 in Chemistry
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- Cytokine production in the brain following closed head injury: dexanabinol (HU-211) is a novel TNF- inhibitor and an effective neuroprotectant (Journal of Neuroimmunology, 1997)
- Efficacy and safety of dexanabinol in severe traumatic brain injury: results of a phase III randomised, placebo-controlled, clinical trial (Lancet Neurology, 2006)
- Dexanabinol (HU-211) in the treatment of severe closed head injury: a randomized, placebo-controlled phase II clinical trial (Critical Care Medicine, 2002)
- Dexanabinol (HU-211) effect on experimental autoimmune encephalomyelitis: implications for the treatment of acute relapses of multiple sclerosis (Journal of Neuroimmunology, 2000)
- PROTECTION AGAINST SEPTIC SHOCK AND SUPPRESSION OF TUMOR NECROSIS FACTOR ALPHA AND NITRIC OXIDE PRODUCTION BY DEXANABINOL (HU-211), A NONPSYCHOTROPIC CANNABINOID (Journal of Pharmacology and Experimental Therapeutics, 1997)
- Dexanabinol; a novel neuroprotective drug in experimental focal cerebral ischemia (Journal of the Neurological Sciences, 1999)
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SMILESCCCCCCC(C)(C)C1=CC2=C(C3CC(=CCC3C(O2)(C)C)CO)C(=C1)O
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InChIKeySSQJFGMEZBFMNV-UHFFFAOYSA-N
- Pubchem - Dexanabinol
- Wikipedia - dexanabinol
Dexanabinol (HU-211 or ETS2101) is a synthetic cannabinoid derivative in development by e-Therapeutics plc. It is the "unnatural" enantiomer of the potent cannabinoid agonist HU-210. Unlike other cannabinoid derivatives, HU-211 does not act as a cannabinoid receptor agonist, but instead has NMDA antagonist effects.
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