| Weight | 442.603 g/mol |
|---|---|
| Formula | C29H34N2O2 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 8 |
DOTARIZINE (84625-59-2)
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Predict GHS Hazards for Any Chemical in silico.
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SMILESC1CN(CCN1CCCC2(OCCO2)C3=CC=CC=C3)C(C4=CC=CC=C4)C5=CC=CC=C5
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InChIKeyLRMJAFKKJLRDLE-UHFFFAOYSA-N
- Pubchem - DOTARIZINE
- Wikipedia - dotarizine
Dotarizine is a drug used in the treatment of migraine, which acts as a calcium channel blocker, and also as an antagonist at the 5HT2A receptor, and to a lesser extent at the 5HT1A and 5HT2C receptors. The anti-migraine action is thought to be due to its action as a vasodilator, but it also has some anxiolytic effects and blocks amnesia produced by electroconvulsive shock in animals.
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