| Weight | 543.525 g/mol |
|---|---|
| Formula | C27H29NO11 |
| Hydrogen Acceptors | 12 |
| Hydrogen Donors | 6 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 5 |
Epirubicin (56420-45-2)
Score:
#108 in Biochemistry
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#172 in Physics
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#468 in Biology
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#489 in Chemistry
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- Significantly Higher Pathologic Complete Remission Rate After Neoadjuvant Therapy With Trastuzumab, Paclitaxel, and Epirubicin Chemotherapy: Results of a Randomized Trial in Human Epidermal Growth Factor Receptor 2Positive Operable Breast Cancer (Journal of Clinical Oncology, 2005)
- Randomized trial comparing epirubicin, cisplatin, and fluorouracil versus fluorouracil, doxorubicin, and methotrexate in advanced esophagogastric cancer. (Journal of Clinical Oncology, 1997)
- Randomized trial of intensive cyclophosphamide, epirubicin, and fluorouracil chemotherapy compared with cyclophosphamide, methotrexate, and fluorouracil in premenopausal women with node-positive breast cancer. National Cancer Institute of Canada Clinical Trials Group. (Journal of Clinical Oncology, 1998)
- Sequential Adjuvant Epirubicin-Based and Docetaxel Chemotherapy for Node-Positive Breast Cancer Patients: The FNCLCC PACS 01 Trial (Journal of Clinical Oncology, 2006)
- Prospective randomized trial comparing mitomycin, cisplatin, and protracted venous-infusion fluorouracil (PVI 5-FU) With epirubicin, cisplatin, and PVI 5-FU in advanced esophagogastric cancer. (Journal of Clinical Oncology, 2002)
- Neoadjuvant Therapy with Paclitaxel followed by 5-Fluorouracil, Epirubicin, and Cyclophosphamide Chemotherapy and Concurrent Trastuzumab in Human Epidermal Growth Factor Receptor 2Positive Operable Breast Cancer: An Update of the Initial Randomized Study Population and Data of Additional Patients Treated with the Same Regimen (Clinical Cancer Research, 2007)
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- Pubchem - Epirubicin
- Wikipedia - epirubicin
Epirubicin is an anthracycline drug used for chemotherapy. It can be used in combination with other medications to treat breast cancer in patients who have had surgery to remove the tumor. It is marketed by Pfizer under the trade name Ellence in the US and Pharmorubicin or Epirubicin Ebewe elsewhere.
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