| Weight | 713.137 g/mol |
|---|---|
| Formula | C34H36MgN6O6S2 |
| Hydrogen Acceptors | 10 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 6 |
| Rotatable Bonds | 10 |
Esomeprazole magnesium
161973-10-0, 95382-33-5, 217087-09-7
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- Clinical trial: the incidence of NSAID-associated endoscopic gastric ulcers in patients treated with PN 400 (naproxen plus esomeprazole magnesium) vs. enteric-coated naproxen alone (Alimentary Pharmacology & Therapeutics, 2010)
- Direct HPLC enantioseparation of omeprazole and its chiral impurities: Application to the determination of enantiomeric purity of esomeprazole magnesium trihydrate (Journal of Pharmaceutical and Biomedical Analysis, 2010)
- Delivery of esomeprazole magnesium enteric-coated pellets through small caliber and standard nasogastric tubes and gastrostomy tubes in vitro. (American Journal of Health-system Pharmacy, 2002)
- A validated stability indicating ultra performance liquid chromatographic method for determination of impurities in Esomeprazole magnesium gastro resistant tablets (Journal of Pharmaceutical and Biomedical Analysis, 2012)
- Clinical trial: evaluation of gastric acid suppression with three doses of immediate-release esomeprazole in the fixed-dose combination of PN 400 (naproxenesomeprazole magnesium) compared with naproxen 500 mg and enteric-coated esomeprazole 20 mg: a randomized, open-label, Phase I study in healthy volunteers (Alimentary Pharmacology & Therapeutics, 2010)
- A fixed-dose combination of naproxen and esomeprazole magnesium has comparable upper gastrointestinal tolerability to celecoxib in patients with osteoarthritis of the knee: Results from two randomized, parallel-group, placebo-controlled trials (Annals of Medicine, 2011)
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SMILESCC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC.CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC.[Mg+2]
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InChIKeyKWORUUGOSLYAGD-UHFFFAOYSA-N
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