| Weight | 409.432 g/mol |
|---|---|
| Formula | C24H21F2NO3 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 6 |
Ezetimibe (163222-33-1)
Score:
#247 in Biochemistry
,
#941 in Biology
,
#1041 in Chemistry
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- Sigma-Aldrich - Ezetimibe96.00 - 595.35 USD
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- The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection) : a randomised placebo-controlled trial (The Lancet, 2011)
- Simvastatin with or without Ezetimibe in Familial Hypercholesterolemia (The New England Journal of Medicine, 2008)
- Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes (The New England Journal of Medicine, 2015)
- Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis. (The New England Journal of Medicine, 2008)
- Extended-Release Niacin or Ezetimibe and Carotid IntimaMedia Thickness (The New England Journal of Medicine, 2009)
- Effect of Ezetimibe Coadministered With Atorvastatin in 628 Patients With Primary Hypercholesterolemia A Prospective, Randomized, Double-Blind Trial (Circulation, 2003)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1=CC(=CC=C1C2C(C(=O)N2C3=CC=C(C=C3)F)CCC(C4=CC=C(C=C4)F)O)O
-
InChIKeyOLNTVTPDXPETLC-UHFFFAOYSA-N
- Pubchem - Ezetimibe
- Wikipedia - ezetimibe
Ezetimibe is a drug that lowers plasma cholesterol levels. It acts by decreasing cholesterol absorption in the small intestine. It may be used alone (marketed as Zetia or Ezetrol), when other cholesterol-lowering medications are not tolerated, or together with statins (e.g., ezetimibe/simvastatin, marketed as Vytorin or Inegy) when statins alone do not control cholesterol.
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